Cargando…

Concealed driver in lung adenocarcinoma with single PIK3CA mutation: a case report and single-center genotyping review

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA) mutation has a prevalence of approximately 2% in lung adenocarcinoma. However, cases presenting a PIK3CA mutation alone have rarely been reported, and the clinical significance of a single PIK3CA mutation has not been we...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Feng, Li, Jianfu, Li, Caichen, Xiong, Shan, Chen, Zhuxing, Cheng, Bo, Zhong, Ran, Liang, Wenhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2021
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940953/ https://www.ncbi.nlm.nih.gov/pubmed/33708898 http://dx.doi.org/10.21037/atm-20-5948

Ejemplares similares

Non-small cell lung cancer with MET exon 14 skipping alteration responding to immunotherapy: a case report
por: Chen, Zhuxing, et al.
Publicado: (2021)

Management for Residual Ground-Glass Opacity Lesions After Resection of Main Tumor in Multifocal Lung Cancer: A Case Report and Literature Review
por: Cheng, Bo, et al.
Publicado: (2021)

The association between CD8+ tumor-infiltrating lymphocytes and the clinical outcome of cancer immunotherapy: A systematic review and meta-analysis
por: Li, Feng, et al.
Publicado: (2021)

Development and validation of a deep transfer learning-based multivariable survival model to predict overall survival in lung cancer
por: Zhu, Feng, et al.
Publicado: (2023)

Mutations of PIK3CA in gastric adenocarcinoma
por: Li, Vivian Sze Wing, et al.
Publicado: (2005)

Preoperative immunochemotherapy for locally advanced non-small cell lung cancer: an analysis of the clinical outcomes, optimal number of cycles, and peripheral immune markers
por: Deng, Hongsheng, et al.
Publicado: (2022)

Dynamic monitoring serum tumor markers to predict molecular features of EGFR‐mutated lung cancer during targeted therapy
por: Chen, Zhuxing, et al.
Publicado: (2022)

Dissection of PIK3CA Aberration for Cervical Adenocarcinoma Outcomes
por: Chung, Tony K. H., et al.
Publicado: (2021)

Predilection site and risk factor of second primary cancer: A pan-cancer analysis based on the SEER database
por: Xiong, Shan, et al.
Publicado: (2023)

Single Nucleotide Polymorphism rs17849071 G/T in the PIK3CA Gene Is Inversely Associated with Follicular Thyroid Cancer and PIK3CA Amplification
por: Xing, Jeffrey C., et al.
Publicado: (2012)

“Major pathologic response” in lymph nodes: a modified nodal classification for non-small cell lung cancer patients treated with neoadjuvant immunochemotherapy
por: Deng, Hongsheng, et al.
Publicado: (2023)

Activation of circ_0072088/miR‐1261/PIK3CA pathway accelerates lung adenocarcinoma progression
por: Cao, Feng, et al.
Publicado: (2022)

PIK3CA Genotype and a PIK3CA Mutation-Related Gene Signature and Response to Everolimus and Letrozole in Estrogen Receptor Positive Breast Cancer
por: Loi, Sherene, et al.
Publicado: (2013)

PIK3CA gene mutation associated with poor prognosis of lung adenocarcinoma
por: Zhang, Lina, et al.
Publicado: (2013)

Carcinogenesis of PIK3CA
por: German, Sidra, et al.
Publicado: (2013)

PD-L1 expression with respect to driver mutations in non-small cell lung cancer in an Asian population: a large study of 1370 cases in China
por: Li, Caichen, et al.
Publicado: (2020)

Correction: PIK3CA Genotype and a PIK3CA Mutation-Related Gene Signature and Response to Everolimus and Letrozole in Estrogen Receptor Positive Breast Cancer
por: Loi, Sherene, et al.
Publicado: (2019)

Novel evidence revealed genetic association between COVID-19 infection, severity and endometrial cancer
por: Wu, Xiangrong, et al.
Publicado: (2022)

Gout and susceptibility and severity of COVID-19: A bidirectional Mendelian randomization analysis
por: Peng, Haoxin, et al.
Publicado: (2022)

Delineation of the phenotypes and genotypes of facial infiltrating lipomatosis associated with PIK3CA mutations
por: Chen, Hongrui, et al.
Publicado: (2023)

Mutation and prognostic analyses of PIK3CA in patients with completely resected lung adenocarcinoma
por: Song, Zhengbo, et al.
Publicado: (2016)

Lung cancers and pulmonary nodules detected by computed tomography scan: a population-level analysis of screening cohorts
por: Li, Caichen, et al.
Publicado: (2021)

DNA methylation markers that correlate with occult lymph node metastases of non-small cell lung cancer and a preliminary prediction model
por: Chen, Zisheng, et al.
Publicado: (2020)

The impact of postoperative EGFR-TKIs treatment on residual GGO lesions after resection for lung cancer
por: Cheng, Bo, et al.
Publicado: (2021)

Prognostic and predictive impact of creatine kinase level in non-small cell lung cancer treated with tyrosine kinase inhibitors
por: Jiang, Yu, et al.
Publicado: (2021)

PIK3CA in Colorectal Cancer
por: Cathomas, Gieri
Publicado: (2014)

Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients
por: Chen, Li, et al.
Publicado: (2018)

Multiplex immunofluorescence and single‐cell transcriptomic profiling reveal the spatial cell interaction networks in the non‐small cell lung cancer microenvironment
por: Peng, Haoxin, et al.
Publicado: (2023)

PIK3CA and KRAS Amplification in Esophageal Adenocarcinoma and their Impact on the Inflammatory Tumor Microenvironment and Prognosis
por: Essakly, Ahlem, et al.
Publicado: (2019)

Diagnostic Accuracy of Droplet Digital PCR and Amplification Refractory Mutation System PCR for Detecting EGFR Mutation in Cell-Free DNA of Lung Cancer: A Meta-Analysis
por: Li, Caichen, et al.
Publicado: (2020)

Characterization of Driver Mutations in Anaplastic Thyroid Carcinoma Identifies RAS and PIK3CA Mutations as Negative Survival Predictors
por: Lai, Wei-An, et al.
Publicado: (2020)

Mutations in PIK3CA are infrequent in neuroblastoma
por: Dam, Vincent, et al.
Publicado: (2006)

PIK3CA-mutations in breast cancer
por: Reinhardt, Kristin, et al.
Publicado: (2022)

Concealed index for concealed penis in prepubertal children
por: Ergashev, Kobiljon, et al.
Publicado: (2021)

An annual review of the remarkable advances in lung cancer clinical research in 2019
por: Cheng, Bo, et al.
Publicado: (2020)

Case Report: Kaposiform hemangioendothelioma with PIK3CA mutation successfully treated with sirolimus
por: Wang, Zuopeng, et al.
Publicado: (2023)

Improved survival associated with somatic PIK3CA mutations in copy-number low endometrioid endometrial adenocarcinoma
por: LIN, DOUGLAS I.
Publicado: (2015)

Hepatoid adenocarcinoma of the stomach with PIK3Ca mutation during pregnancy: A case report with molecular profile
por: Ranceva, Anastasija, et al.
Publicado: (2021)

Mutation of the PIK3CA oncogene in human cancers
por: Karakas, B, et al.
Publicado: (2006)

Initiating breast cancer by PIK3CA mutation
por: Miller, Todd W
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_3hlf7v91b0i9h8s58o62f669bn