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Ca(2+) Sensitivity of Anoctamin 6/TMEM16F Is Regulated by the Putative Ca(2+)-Binding Reservoir at the N-Terminal Domain
Anoctamin 6/TMEM16F (ANO6) is a dual-function protein with Ca(2+)-activated ion channel and Ca(2+)-activated phospholipid scramblase activities, requiring a high intracellular Ca(2+) concentration (e.g., half-maximal effective Ca(2+) concentration [EC(50)] of [Ca(2+)](i) > 10 μM), and strong and...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Korean Society for Molecular and Cellular Biology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941003/ https://www.ncbi.nlm.nih.gov/pubmed/33658434 http://dx.doi.org/10.14348/molcells.2021.2203 |