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Stepwise candidate drug screening for myopia control by using zebrafish, mouse, and Golden Syrian Hamster myopia models

BACKGROUND: We developed a preclinical protocol for the screening of candidate drugs able to control myopia and prevent its progression. The protocol uses zebrafish, C57BL/6 mice, and golden Syrian hamster models of myopia. METHODS: A morpholino (MO) targeting the zebrafish lumican gene (zlum) was i...

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Detalles Bibliográficos
Autores principales:	Lin, Meng-Yin, Lin, I-Tsen, Wu, Yu-Ching, Wang, I-Jong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941086/ https://www.ncbi.nlm.nih.gov/pubmed/33691248 http://dx.doi.org/10.1016/j.ebiom.2021.103263

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