Do we cause false positives? An experimental series on droplet or airborne SARS-CoV-2 contamination of sampling tubes during swab collection in a test center

The rapid spread of the coronavirus disease 2019 pandemic urged immense testing capacities as one cornerstone of infection control. Many institutions opened outpatient SARS-CoV-2 test centers to allow large number of tests in comparatively short time frames. With increasing positive test rates, conc...

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Autores principales: Scheier, Thomas, Shah, Cyril, Huber, Michael, Sax, Hugo, Hasse, Barbara, Günthard, Huldrych F., Trkola, Alexandra, Schreiber, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941134/
https://www.ncbi.nlm.nih.gov/pubmed/33750477
http://dx.doi.org/10.1186/s13756-021-00920-z
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author Scheier, Thomas
Shah, Cyril
Huber, Michael
Sax, Hugo
Hasse, Barbara
Günthard, Huldrych F.
Trkola, Alexandra
Schreiber, Peter W.
author_facet Scheier, Thomas
Shah, Cyril
Huber, Michael
Sax, Hugo
Hasse, Barbara
Günthard, Huldrych F.
Trkola, Alexandra
Schreiber, Peter W.
author_sort Scheier, Thomas
collection PubMed
description The rapid spread of the coronavirus disease 2019 pandemic urged immense testing capacities as one cornerstone of infection control. Many institutions opened outpatient SARS-CoV-2 test centers to allow large number of tests in comparatively short time frames. With increasing positive test rates, concerns for a possible airborne or droplet contamination of specimens leading to false-positive results were raised. In our experimental series performed in a dedicated SARS-CoV-2 test center, 40 open collection tubes placed for defined time periods in proximity to individuals were found to be SARS-CoV-2 negative. These findings argue against false-positive SARS-CoV-2 results due to droplet or airborne contamination.
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spelling pubmed-79411342021-03-09 Do we cause false positives? An experimental series on droplet or airborne SARS-CoV-2 contamination of sampling tubes during swab collection in a test center Scheier, Thomas Shah, Cyril Huber, Michael Sax, Hugo Hasse, Barbara Günthard, Huldrych F. Trkola, Alexandra Schreiber, Peter W. Antimicrob Resist Infect Control Short Report The rapid spread of the coronavirus disease 2019 pandemic urged immense testing capacities as one cornerstone of infection control. Many institutions opened outpatient SARS-CoV-2 test centers to allow large number of tests in comparatively short time frames. With increasing positive test rates, concerns for a possible airborne or droplet contamination of specimens leading to false-positive results were raised. In our experimental series performed in a dedicated SARS-CoV-2 test center, 40 open collection tubes placed for defined time periods in proximity to individuals were found to be SARS-CoV-2 negative. These findings argue against false-positive SARS-CoV-2 results due to droplet or airborne contamination. BioMed Central 2021-03-09 /pmc/articles/PMC7941134/ /pubmed/33750477 http://dx.doi.org/10.1186/s13756-021-00920-z Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Short Report
Scheier, Thomas
Shah, Cyril
Huber, Michael
Sax, Hugo
Hasse, Barbara
Günthard, Huldrych F.
Trkola, Alexandra
Schreiber, Peter W.
Do we cause false positives? An experimental series on droplet or airborne SARS-CoV-2 contamination of sampling tubes during swab collection in a test center
title Do we cause false positives? An experimental series on droplet or airborne SARS-CoV-2 contamination of sampling tubes during swab collection in a test center
title_full Do we cause false positives? An experimental series on droplet or airborne SARS-CoV-2 contamination of sampling tubes during swab collection in a test center
title_fullStr Do we cause false positives? An experimental series on droplet or airborne SARS-CoV-2 contamination of sampling tubes during swab collection in a test center
title_full_unstemmed Do we cause false positives? An experimental series on droplet or airborne SARS-CoV-2 contamination of sampling tubes during swab collection in a test center
title_short Do we cause false positives? An experimental series on droplet or airborne SARS-CoV-2 contamination of sampling tubes during swab collection in a test center
title_sort do we cause false positives? an experimental series on droplet or airborne sars-cov-2 contamination of sampling tubes during swab collection in a test center
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941134/
https://www.ncbi.nlm.nih.gov/pubmed/33750477
http://dx.doi.org/10.1186/s13756-021-00920-z
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