Cell-type-specific imaging of neurotransmission reveals a disrupted excitatory-inhibitory cortical network in isoflurane anaesthesia

BACKGROUND: Despite the fundamental clinical significance of general anaesthesia, the cortical mechanism underlying anaesthetic-induced loss of consciousness (aLOC) remains elusive. METHODS: Here, we measured the dynamics of two major cortical neurotransmitters, gamma-aminobutyric acid (GABA) and gl...

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Detalles Bibliográficos
Autores principales: Guo, Juan, Ran, Mingzi, Gao, Zilong, Zhang, Xinxin, Wang, Dan, Li, Huiming, Zhao, Shiyi, Sun, Wenzhi, Dong, Hailong, Hu, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941179/
https://www.ncbi.nlm.nih.gov/pubmed/33691246
http://dx.doi.org/10.1016/j.ebiom.2021.103272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941179/
https://www.ncbi.nlm.nih.gov/pubmed/33691246
http://dx.doi.org/10.1016/j.ebiom.2021.103272

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