Cargando…

Cell-type-specific imaging of neurotransmission reveals a disrupted excitatory-inhibitory cortical network in isoflurane anaesthesia

BACKGROUND: Despite the fundamental clinical significance of general anaesthesia, the cortical mechanism underlying anaesthetic-induced loss of consciousness (aLOC) remains elusive. METHODS: Here, we measured the dynamics of two major cortical neurotransmitters, gamma-aminobutyric acid (GABA) and gl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Juan, Ran, Mingzi, Gao, Zilong, Zhang, Xinxin, Wang, Dan, Li, Huiming, Zhao, Shiyi, Sun, Wenzhi, Dong, Hailong, Hu, Ji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941179/ https://www.ncbi.nlm.nih.gov/pubmed/33691246 http://dx.doi.org/10.1016/j.ebiom.2021.103272

Ejemplares similares

Frequency-Dependent Block of Excitatory Neurotransmission by Isoflurane via Dual Presynaptic Mechanisms
por: Wang, Han-Ying, et al.
Publicado: (2020)

Reduced excitatory neurotransmission in the hippocampus after inflammation and sevoflurane anaesthesia
por: Khodaei, Shahin, et al.
Publicado: (2023)

Isoflurane anesthesia disrupts the cortical metabolome
por: Baer, Aaron G., et al.
Publicado: (2020)

Glycine receptor autoantibodies disrupt inhibitory neurotransmission
por: Crisp, Sarah J, et al.
Publicado: (2019)

Role of the neuronal K-Cl co-transporter KCC2 in inhibitory and excitatory neurotransmission
por: Chamma, Ingrid, et al.
Publicado: (2012)

Enhancement of inhibitory neurotransmission and inhibition of excitatory mechanisms underlie the anticonvulsant effects of Mallotus oppositifolius
por: Kukuia, Kennedy Kwami Edem, et al.
Publicado: (2016)

Interstitial cells of Cajal link excitatory and nitrergic inhibitory neurotransmission with slow-wave activity in the intestine
por: Klein, Sabine, et al.
Publicado: (2013)

Neuroplasticity of excitatory and inhibitory cortical circuits in schizophrenia
por: Lewis, David A.
Publicado: (2009)

Dorsal raphe serotonergic neurons promote arousal from isoflurane anesthesia
por: Li, Ao, et al.
Publicado: (2021)

Astrocytic GABA transporter activity modulates excitatory neurotransmission
por: Boddum, Kim, et al.
Publicado: (2016)

Lateral Hypothalamic Area Glutamatergic Neurons and Their Projections to the Lateral Habenula Modulate the Anesthetic Potency of Isoflurane in Mice
por: Zhao, Shiyi, et al.
Publicado: (2021)

Tracking the Expression of Excitatory and Inhibitory Neurotransmission-Related Proteins and Neuroplasticity Markers after Noise Induced Hearing Loss
por: Browne, Cherylea J., et al.
Publicado: (2012)

Altered neural connectivity in excitatory and inhibitory cortical circuits in autism
por: Zikopoulos, Basilis, et al.
Publicado: (2013)

The Influence of Isoflurane Anaesthesia on the Rat Grimace Scale
por: Miller, Amy L., et al.
Publicado: (2016)

Intraoperative wandering atrial pacemaker with isoflurane anaesthesia
por: Bhattacharjee, Sulagna, et al.
Publicado: (2016)

Energetics of Excitatory and Inhibitory Neurotransmission in Aluminum Chloride Model of Alzheimer’s Disease: Reversal of Behavioral and Metabolic Deficits by Rasa Sindoor
por: Saba, Kamal, et al.
Publicado: (2017)

Subcellular sorting of neuregulins controls the assembly of excitatory-inhibitory cortical circuits
por: Exposito-Alonso, David, et al.
Publicado: (2020)

Effects of isoflurane and urethane anesthetics on glutamate neurotransmission in rat brain using in vivo amperometry
por: Beitchman, Joshua A., et al.
Publicado: (2023)

Effects of isoflurane and urethane anesthetics on glutamate neurotransmission in rat brain using in vivo amperometry
por: Beitchman, Joshua A., et al.
Publicado: (2023)

Excitatory-inhibitory balance modulates the formation and dynamics of neuronal assemblies in cortical networks
por: Sadeh, Sadra, et al.
Publicado: (2021)

Probing the link between cortical inhibitory and excitatory processes and muscle fascicle dynamics
por: Lauber, Benedikt, et al.
Publicado: (2023)

The Role of SUMO-Conjugating Enzyme Ubc9 in the Neuroprotection of Isoflurane Preconditioning Against Ischemic Neuronal Injury
por: Tong, Li, et al.
Publicado: (2014)

Comparison of Systemic Effects of Midazolam, Ketamine, and Isoflurane Anaesthesia in Rabbits
por: Atalan, Güneri, et al.
Publicado: (2019)

Amphiphilic anti-SARS-CoV-2 drug remdesivir incorporates into the lipid bilayer and nerve terminal membranes influencing excitatory and inhibitory neurotransmission
por: Krisanova, Natalia, et al.
Publicado: (2022)

Isoflurane suppresses early cortical activity
por: Sitdikova, Guzel, et al.
Publicado: (2014)

A Homolog of FHM2 Is Involved in Modulation of Excitatory Neurotransmission by Serotonin in C. elegans
por: Govorunova, Elena G., et al.
Publicado: (2010)

Chemogenetic Activation of Excitatory Neurons Alters Hippocampal Neurotransmission in a Dose-Dependent Manner
por: Pati, Sthitapranjya, et al.
Publicado: (2019)

Differential effects of excitatory and inhibitory heterogeneity on the gain and asynchronous state of sparse cortical networks
por: Mejias, Jorge F., et al.
Publicado: (2014)

Multiscale effects of excitatory-inhibitory homeostasis in lesioned cortical networks: A computational study
por: Páscoa dos Santos, Francisco, et al.
Publicado: (2023)

A Comparative Study of Propofol and Isoflurane Anaesthesia using Butorphanol in Neurosurgery
por: Mishra, LD, et al.
Publicado: (2009)

Depth of Anaesthesia Associated with 2.5% Isoflurane During Cardiopulmonary Bypass
por: Connelly, Michael D, et al.
Publicado: (2015)

Long-term surgical anaesthesia with isoflurane in human habituated Nile Crocodiles
por: Stegmann, George F., et al.
Publicado: (2017)

Impact of general anaesthesia on endoplasmic reticulum stress: propofol vs. isoflurane
por: Seo, Eun-Hye, et al.
Publicado: (2019)

Neurotoxicity of different amyloid beta subspecies in mice and their interaction with isoflurane anaesthesia
por: Borgstedt, Laura, et al.
Publicado: (2020)

Intraoperative Assessment of Fluid Responsiveness in Normotensive Dogs under Isoflurane Anaesthesia
por: Skouropoulou, Despoina, et al.
Publicado: (2021)

Cortical cells reveal APP as a new player in the regulation of GABAergic neurotransmission
por: Doshina, Anna, et al.
Publicado: (2017)

Multimodal electrophysiological analyses reveal that reduced synaptic excitatory neurotransmission underlies seizures in a model of NMDAR antibody-mediated encephalitis
por: Wright, Sukhvir K., et al.
Publicado: (2021)

Impaired Excitatory Neurotransmission in the Urinary Bladder from the Obese Zucker Rat: Role of Cannabinoid Receptors
por: Blaha, Igor, et al.
Publicado: (2016)

Inhibitory control of the excitatory/inhibitory balance in psychiatric disorders
por: Selten, Martijn, et al.
Publicado: (2018)

MEF2C regulates cortical inhibitory and excitatory synapses and behaviors relevant to neurodevelopmental disorders
por: Harrington, Adam J, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_ie39ndjit2a8oahcr0v2cu85nm