Sirtuin 1 ameliorates defenestration in hepatic sinusoidal endothelial cells during liver fibrosis via inhibiting stress‐induced premature senescence

OBJECTIVE: Premature senescence is related to progerin and involves in endothelial dysfunction and liver diseases. Activating sirtuin 1 (SIRT1) ameliorates liver fibrosis. However, the mechanisms of premature senescence in defenestration of hepatic sinusoidal endothelial cells (HSECs) and how SIRT1...

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Detalles Bibliográficos
Autores principales: Luo, Xiaoying, Bai, Yangqiu, He, Shuli, Sun, Suofeng, Jiang, Xiaoke, Yang, Zhiyu, Lu, Di, Wei, Peiru, Liang, Yuan, Peng, Cong, Wang, Yaru, Sheng, Ruli, Han, Shuangyin, Li, Xiuling, Zhang, Bingyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941223/
https://www.ncbi.nlm.nih.gov/pubmed/33522656
http://dx.doi.org/10.1111/cpr.12991

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