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Tripe palms and Malignant Acanthosis Nigricans: More than a diagnostic pointer

BACKGROUND: Tripe palms (TP) is one of the rare cutaneous paraneoplastic manifestations of various intra‐abdominal malignancies. TP and malignant acanthosis nigricans (MAN) occur together and may precede even years before the index cancer. Though rare, the clinical significance of TP and MAN holds s...

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Autores principales: Kumar, Parmod, Mukundan, Megha K, Sehrawat, Amit, Sundriyal, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941556/
https://www.ncbi.nlm.nih.gov/pubmed/33074559
http://dx.doi.org/10.1002/cnr2.1307
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author Kumar, Parmod
Mukundan, Megha K
Sehrawat, Amit
Sundriyal, Deepak
author_facet Kumar, Parmod
Mukundan, Megha K
Sehrawat, Amit
Sundriyal, Deepak
author_sort Kumar, Parmod
collection PubMed
description BACKGROUND: Tripe palms (TP) is one of the rare cutaneous paraneoplastic manifestations of various intra‐abdominal malignancies. TP and malignant acanthosis nigricans (MAN) occur together and may precede even years before the index cancer. Though rare, the clinical significance of TP and MAN holds significance as an indicator of internal malignancy. CASE: Here, we describe 71‐year, postmenopausal female with ovarian cancer who presented to us with a history of dyspepsia, abdominal distension, and weight loss. On detailed history and evaluation, it was found that she had TP and MAN 4 years before diagnosis. CONCLUSION: The unique presentation preceding the primary illness necessitates extensive early work‐up to look for malignancy and the initial consideration for surgery due to the tumor biology in such patients.
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spelling pubmed-79415562021-05-10 Tripe palms and Malignant Acanthosis Nigricans: More than a diagnostic pointer Kumar, Parmod Mukundan, Megha K Sehrawat, Amit Sundriyal, Deepak Cancer Rep (Hoboken) Case Reports BACKGROUND: Tripe palms (TP) is one of the rare cutaneous paraneoplastic manifestations of various intra‐abdominal malignancies. TP and malignant acanthosis nigricans (MAN) occur together and may precede even years before the index cancer. Though rare, the clinical significance of TP and MAN holds significance as an indicator of internal malignancy. CASE: Here, we describe 71‐year, postmenopausal female with ovarian cancer who presented to us with a history of dyspepsia, abdominal distension, and weight loss. On detailed history and evaluation, it was found that she had TP and MAN 4 years before diagnosis. CONCLUSION: The unique presentation preceding the primary illness necessitates extensive early work‐up to look for malignancy and the initial consideration for surgery due to the tumor biology in such patients. John Wiley and Sons Inc. 2020-10-19 /pmc/articles/PMC7941556/ /pubmed/33074559 http://dx.doi.org/10.1002/cnr2.1307 Text en © 2020 The Authors. Cancer Reports published by Wiley Periodicals LLC. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Kumar, Parmod
Mukundan, Megha K
Sehrawat, Amit
Sundriyal, Deepak
Tripe palms and Malignant Acanthosis Nigricans: More than a diagnostic pointer
title Tripe palms and Malignant Acanthosis Nigricans: More than a diagnostic pointer
title_full Tripe palms and Malignant Acanthosis Nigricans: More than a diagnostic pointer
title_fullStr Tripe palms and Malignant Acanthosis Nigricans: More than a diagnostic pointer
title_full_unstemmed Tripe palms and Malignant Acanthosis Nigricans: More than a diagnostic pointer
title_short Tripe palms and Malignant Acanthosis Nigricans: More than a diagnostic pointer
title_sort tripe palms and malignant acanthosis nigricans: more than a diagnostic pointer
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941556/
https://www.ncbi.nlm.nih.gov/pubmed/33074559
http://dx.doi.org/10.1002/cnr2.1307
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