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The mRNA-LNP platform’s lipid nanoparticle component used in preclinical vaccine studies is highly inflammatory
Vaccines based on mRNA-containing lipid nanoparticles (LNPs) are a promising new platform used by two leading vaccines against coronavirus disease in 2019 (COVID-19). Clinical trials and ongoing vaccinations present with very high protection levels and varying degrees of side effects. However, the n...
Autores principales: | Ndeupen, Sonia, Qin, Zhen, Jacobsen, Sonya, Estanbouli, Henri, Bouteau, Aurélie, Igyártó, Botond Z. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941620/ https://www.ncbi.nlm.nih.gov/pubmed/33688649 http://dx.doi.org/10.1101/2021.03.04.430128 |
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