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Negligible impact of SARS-CoV-2 variants on CD4(+) and CD8(+) T cell reactivity in COVID-19 exposed donors and vaccinees.

The emergence of SARS-CoV-2 variants highlighted the need to better understand adaptive immune responses to this virus. It is important to address whether also CD4+ and CD8+ T cell responses are affected, because of the role they play in disease resolution and modulation of COVID-19 disease severity...

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Detalles Bibliográficos
Autores principales:	Tarke, Alison, Sidney, John, Methot, Nils, Zhang, Yun, Dan, Jennifer M., Goodwin, Benjamin, Rubiro, Paul, Sutherland, Aaron, da Silva Antunes, Ricardo, Frazier, April, Rawlings, Stephen A., Smith, Davey M., Peters, Bjoern, Scheuermann, Richard H., Weiskopf, Daniela, Crotty, Shane, Grifoni, Alba, Sette, Alessandro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941626/ https://www.ncbi.nlm.nih.gov/pubmed/33688655 http://dx.doi.org/10.1101/2021.02.27.433180

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