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Pyk2 overexpression in postsynaptic neurons blocks amyloid β(1–42)-induced synaptotoxicity in microfluidic co-cultures
Recent meta-analyses of genome-wide association studies identified a number of genetic risk factors of Alzheimer’s disease; however, little is known about the mechanisms by which they contribute to the pathological process. As synapse loss is observed at the earliest stage of Alzheimer’s disease, de...
Autores principales: | Kilinc, Devrim, Vreulx, Anaïs-Camille, Mendes, Tiago, Flaig, Amandine, Marques-Coelho, Diego, Verschoore, Maxime, Demiautte, Florie, Amouyel, Philippe, Eysert, Fanny, Dourlen, Pierre, Chapuis, Julien, Costa, Marcos R, Malmanche, Nicolas, Checler, Frédéric, Lambert, Jean-Charles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941669/ https://www.ncbi.nlm.nih.gov/pubmed/33718872 http://dx.doi.org/10.1093/braincomms/fcaa139 |
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