Cargando…

Identification of Biomarkers Based on Bioinformatics Analysis: The Expression of Ubiquitin-Conjugating Enzyme E2T (UBE2T) in the Carcinogenesis and Progression of Hepatocellular Carcinoma

BACKGROUND: The purpose of this study was to screen and identify key genes in the occurrence and development of hepatocellular carcinoma (HCC) based on bioinformatics analysis. MATERIAL/METHODS: Three Gene Expression Omnibus (GEO) series (GSE) – GSE121248, GSE87630, and GSE84598 – were downloaded fr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Xuemiao, Weng, Wei, Jin, Miao, Li, Sunjian, Chen, Qingwei, Li, Bingrong, Zhou, Zhou, Lan, Chuanqiang, Yang, Yunjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2021
Materias:	Database Analysis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941760/ https://www.ncbi.nlm.nih.gov/pubmed/33658475 http://dx.doi.org/10.12659/MSM.929023

Ejemplares similares

Conformational Dynamics Modulate Activation of the Ubiquitin Conjugating Enzyme Ube2g2
por: Magala, Pearl, et al.
Publicado: (2017)

Sex Differences in Osteoarthritis Pathogenesis: A Comprehensive Study Based on Bioinformatics
por: Yang, Yunfeng, et al.
Publicado: (2020)

iUUCD 2.0: an update with rich annotations for ubiquitin and ubiquitin-like conjugations
por: Zhou, Jiaqi, et al.
Publicado: (2018)

Ubiquitin-Conjugating Enzyme UBE2C Is Highly Expressed in Breast Microcalcification Lesions
por: Chou, Chen-Pin, et al.
Publicado: (2014)

Loss of the ubiquitin conjugating enzyme UBE2E3 induces cellular senescence
por: Plafker, Kendra S., et al.
Publicado: (2018)

Allosteric Targeting of the Fanconi Anemia Ubiquitin-Conjugating Enzyme Ube2T by Fragment Screening
por: Morreale, Francesca E., et al.
Publicado: (2017)

Crystal Structure of a Ube2S-Ubiquitin Conjugate
por: Lorenz, Sonja, et al.
Publicado: (2016)

Mechanism and Disease Association With a Ubiquitin Conjugating E2 Enzyme: UBE2L3
por: Zhang, Xiaoxia, et al.
Publicado: (2022)

H2A Histone Family Member Z (H2AFZ) Serves as a Prognostic Biomarker in Lung Adenocarcinoma: Bioinformatic Analysis and Experimental Validation
por: Li, Zongkuo, et al.
Publicado: (2022)

Identification of Target Genes and Transcription Factors in Mice with LMNA-Related Dilated Cardiomyopathy by Integrated Bioinformatic Analyses
por: Zhou, Honghua, et al.
Publicado: (2020)

The E2 ubiquitin-conjugating enzymes UBE2D1 and UBE2D2 regulate VEGFR2 dynamics and endothelial function
por: Critchley, William R., et al.
Publicado: (2023)

Bioinformatic Profiling of Prognosis-Related Genes in Malignant Glioma Microenvironment
por: Li, Yong, et al.
Publicado: (2020)

Identification of Potential Biomarkers Associated with Prognosis in Gastric Cancer via Bioinformatics Analysis
por: Li, Dong, et al.
Publicado: (2021)

Comprehensive Analysis of Fibroblast Growth Factor Receptor (FGFR) Family Genes in Breast Cancer by Integrating Online Databases and Bioinformatics
por: Zhou, Zhaoping, et al.
Publicado: (2020)

The ubiquitin‐conjugating enzyme UBE2QL1 coordinates lysophagy in response to endolysosomal damage
por: Koerver, Lisa, et al.
Publicado: (2019)

The UBE2D ubiquitin conjugating enzymes: Potential regulatory hubs in development, disease and evolution
por: Roman-Trufero, Monica, et al.
Publicado: (2022)

Molecular Mechanisms Underlying Intestinal Ischemia/Reperfusion Injury: Bioinformatics Analysis and In Vivo Validation
por: Chen, Fengshou, et al.
Publicado: (2020)

Bioinformatics Identification of Candidate Biomarkers in Endomyocardial Biopsy and Peripheral Blood for Cardiac Allograft Rejection
por: Luo, Kang, et al.
Publicado: (2022)

Bioinformatics Analysis for Multiple Gene Expression Profiles in Sepsis
por: Zhai, Jianhua, et al.
Publicado: (2020)

Estimation of Hub Genes and Infiltrating Immune Cells in Non-Smoking Females with Lung Adenocarcinoma by Integrated Bioinformatic Analysis
por: Li, Jie, et al.
Publicado: (2020)

Bioinformatics-Based Study to Investigate Potential Differentially Expressed Genes and miRNAs in Pediatric Sepsis
por: Xie, Kexin, et al.
Publicado: (2020)

Upregulation of ubiquitin-conjugating enzyme E2T (UBE2T) predicts poor prognosis and promotes hepatocellular carcinoma progression
por: Ren, Xiaoyue, et al.
Publicado: (2021)

Integrated Analysis of Angiogenesis-Mediated Tumor Immune Microenvironment Pattern in Hepatocellular Carcinoma (HCC) and a Novel Prognostic Model Construction to Predict Patient Outcome
por: Lv, Chengqian, et al.
Publicado: (2021)

Bioinformatics for The Prognostic Value and Function of Cubilin (CUBN) in Colorectal Cancer
por: Wu, Yibin, et al.
Publicado: (2020)

Integrated Bioinformatic Analysis of Competing Endogenous RNA Network of Choriocarcinoma
por: Tan, Qianxia, et al.
Publicado: (2021)

Sirtuin 3 mRNA Expression is Downregulated in the Brain Tissues of Alzheimer’s Disease Patients: A Bioinformatic and Data Mining Approach
por: Song, Shuang, et al.
Publicado: (2020)

Integrated Bioinformatics Analysis Reveals Potential Pathway Biomarkers and Their Interactions for Clubfoot
por: Ding, Jing, et al.
Publicado: (2020)

Identification of Novel Genes and Associated Drugs in Cervical Cancer by Bioinformatics Methods
por: Wang, Dan, et al.
Publicado: (2022)

Transcriptome Analysis of Peripheral Blood Mononuclear Cells Response in Patients with Severe COVID-19 Reveals Crucial Genes Regulating Protein Ubiquitination
por: Huang, Jinfeng, et al.
Publicado: (2022)

High expression of ubiquitin-conjugating enzyme 2C (UBE2C) correlates with nasopharyngeal carcinoma progression
por: Shen, Zhihua, et al.
Publicado: (2013)

Bioinformatics Analysis and Identification of Underlying Biomarkers Potentially Linking Allergic Rhinitis and Asthma
por: Yan, Zhanfeng, et al.
Publicado: (2020)

Identification of Genes with Prognostic Value in the Breast Cancer Microenvironment Using Bioinformatics Analysis
por: Ren, Haoyu, et al.
Publicado: (2020)

Potential Target Genes in the Development of Atrial Fibrillation: A Comprehensive Bioinformatics Analysis
por: Liu, Liang, et al.
Publicado: (2021)

Ubiquitin Conjugating Enzyme E2 H (UBE2H) Is Linked to Poor Outcomes and Metastasis in Lung Adenocarcinoma
por: Yen, Meng-Chi, et al.
Publicado: (2021)

The ubiquitin-conjugating enzyme UBE2O modulates c-Maf stability and induces myeloma cell apoptosis
por: Xu, Yujia, et al.
Publicado: (2017)

Screening and Identification of Potential Peripheral Blood Biomarkers for Alzheimer’s Disease Based on Bioinformatics Analysis
por: Wang, Xin, et al.
Publicado: (2020)

Bioinformatics Analysis of Prognostic Tumor Microenvironment-Related Genes in the Tumor Microenvironment of Hepatocellular Carcinoma
por: Tian, Zongbiao, et al.
Publicado: (2020)

Identification of Key Genes and Underlying Mechanisms in Acute Kawasaki Disease Based on Bioinformatics Analysis
por: Gao, Side, et al.
Publicado: (2021)

COL3A1, COL6A3, and SERPINH1 Are Related to Glucocorticoid-Induced Osteoporosis Occurrence According to Integrated Bioinformatics Analysis
por: Li, Liuxun, et al.
Publicado: (2020)

Identification of Key Genes Associated with Brain Metastasis from Breast Cancer: A Bioinformatics Analysis
por: Zeng, Cheng, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_hv796r27kldheoumobt5ckufb6