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Anterior segment optical coherence tomography imaging and ocular biometry in cataract patients with open angle glaucoma comorbidity

BACKGROUND: Anterior chamber angle anatomy in perspective of ocular biometry may be the key element to intraocular pressure (IOP) reduction, especially in glaucoma patients. We aim to investigate anterior chamber angle and biometrical data prior to cataract surgery in patients with and without glauc...

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Autores principales: Pakuliene, Giedre, Zimarinas, Kirilas, Nedzelskiene, Irena, Siesky, Brent, Kuzmiene, Loreta, Harris, Alon, Januleviciene, Ingrida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941888/
https://www.ncbi.nlm.nih.gov/pubmed/33685443
http://dx.doi.org/10.1186/s12886-021-01874-x
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author Pakuliene, Giedre
Zimarinas, Kirilas
Nedzelskiene, Irena
Siesky, Brent
Kuzmiene, Loreta
Harris, Alon
Januleviciene, Ingrida
author_facet Pakuliene, Giedre
Zimarinas, Kirilas
Nedzelskiene, Irena
Siesky, Brent
Kuzmiene, Loreta
Harris, Alon
Januleviciene, Ingrida
author_sort Pakuliene, Giedre
collection PubMed
description BACKGROUND: Anterior chamber angle anatomy in perspective of ocular biometry may be the key element to intraocular pressure (IOP) reduction, especially in glaucoma patients. We aim to investigate anterior chamber angle and biometrical data prior to cataract surgery in patients with and without glaucoma comorbidity. MATERIALS AND METHODS: This prospective comparative case-control study included 62 subjects (38 with cataract only and 24 with cataract and glaucoma). A full ophthalmic examination including, Goldmann applanation tonometry, anterior chamber swept source optical coherence tomography (DRI OCT Triton plus (Ver.10.13)) and swept source optical biometry (IOL Master 700 v1.7) was performed on all participants. RESULTS: We found that ocular biometry parameters and anterior chamber parameters were not significantly different among groups. However, when we added cut-off values for narrow angles, we found that glaucoma group tended to have more narrow angles than control group. IOP was higher in glaucoma group despite all glaucoma patients having medically controlled IOP. In all subjects, anterior chamber parameters correlated well with lens position (LP), but less with relative lens position, while LP cut-off value of 5.1 mm could be used for predicting narrow anterior chamber angle parameters. CONCLUSIONS: Cataract patients tend to develop narrow anterior chamber angles. Anterior chamber angle parameters have a positive moderate to strong relationship with lens position. LP may be used predicting narrow angles.
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spelling pubmed-79418882021-03-09 Anterior segment optical coherence tomography imaging and ocular biometry in cataract patients with open angle glaucoma comorbidity Pakuliene, Giedre Zimarinas, Kirilas Nedzelskiene, Irena Siesky, Brent Kuzmiene, Loreta Harris, Alon Januleviciene, Ingrida BMC Ophthalmol Research Article BACKGROUND: Anterior chamber angle anatomy in perspective of ocular biometry may be the key element to intraocular pressure (IOP) reduction, especially in glaucoma patients. We aim to investigate anterior chamber angle and biometrical data prior to cataract surgery in patients with and without glaucoma comorbidity. MATERIALS AND METHODS: This prospective comparative case-control study included 62 subjects (38 with cataract only and 24 with cataract and glaucoma). A full ophthalmic examination including, Goldmann applanation tonometry, anterior chamber swept source optical coherence tomography (DRI OCT Triton plus (Ver.10.13)) and swept source optical biometry (IOL Master 700 v1.7) was performed on all participants. RESULTS: We found that ocular biometry parameters and anterior chamber parameters were not significantly different among groups. However, when we added cut-off values for narrow angles, we found that glaucoma group tended to have more narrow angles than control group. IOP was higher in glaucoma group despite all glaucoma patients having medically controlled IOP. In all subjects, anterior chamber parameters correlated well with lens position (LP), but less with relative lens position, while LP cut-off value of 5.1 mm could be used for predicting narrow anterior chamber angle parameters. CONCLUSIONS: Cataract patients tend to develop narrow anterior chamber angles. Anterior chamber angle parameters have a positive moderate to strong relationship with lens position. LP may be used predicting narrow angles. BioMed Central 2021-03-08 /pmc/articles/PMC7941888/ /pubmed/33685443 http://dx.doi.org/10.1186/s12886-021-01874-x Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Pakuliene, Giedre
Zimarinas, Kirilas
Nedzelskiene, Irena
Siesky, Brent
Kuzmiene, Loreta
Harris, Alon
Januleviciene, Ingrida
Anterior segment optical coherence tomography imaging and ocular biometry in cataract patients with open angle glaucoma comorbidity
title Anterior segment optical coherence tomography imaging and ocular biometry in cataract patients with open angle glaucoma comorbidity
title_full Anterior segment optical coherence tomography imaging and ocular biometry in cataract patients with open angle glaucoma comorbidity
title_fullStr Anterior segment optical coherence tomography imaging and ocular biometry in cataract patients with open angle glaucoma comorbidity
title_full_unstemmed Anterior segment optical coherence tomography imaging and ocular biometry in cataract patients with open angle glaucoma comorbidity
title_short Anterior segment optical coherence tomography imaging and ocular biometry in cataract patients with open angle glaucoma comorbidity
title_sort anterior segment optical coherence tomography imaging and ocular biometry in cataract patients with open angle glaucoma comorbidity
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941888/
https://www.ncbi.nlm.nih.gov/pubmed/33685443
http://dx.doi.org/10.1186/s12886-021-01874-x
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