Cargando…

Up-regulation of DGAT1 in cancer tissues and tumor-infiltrating macrophages influenced survival of patients with gastric cancer

BACKGROUND: Diacylglycerol-acyltransferase 1 (DGAT1) plays an important role in the energy storage and is involved in cancer progression. A growing number of evidences showed that elevated expression of DGAT1 in cancer tissue indicated a poor outcome in cancer patients. However, the relationship bet...

Descripción completa

Detalles Bibliográficos
Autores principales:	He, Ping, Cheng, Shihuan, Hu, Feng, Ma, Zhanchuan, Xia, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941926/ https://www.ncbi.nlm.nih.gov/pubmed/33750350 http://dx.doi.org/10.1186/s12885-021-07976-5

Ejemplares similares

Hypoxia-inducible factor-1 alpha Correlates with Tumor-Associated Macrophages Infiltration, Influences Survival of Gastric Cancer Patients
por: Zhang, Wei-jie, et al.
Publicado: (2017)

DGAT1 Expression Promotes Ovarian Cancer Progression and Is Associated with Poor Prognosis
por: Xia, Leilei, et al.
Publicado: (2021)

The triglyceride synthesis enzymes DGAT1 and DGAT2 have distinct and overlapping functions in adipocytes
por: Chitraju, Chandramohan, et al.
Publicado: (2019)

Tumor Infiltrating Lymphocytes and Macrophages Improve Survival in Microsatellite Unstable Colorectal Cancer
por: Narayanan, Sumana, et al.
Publicado: (2019)

High Infiltration of Tumor-Associated Macrophages Influences Poor Prognosis in Human Gastric Cancer Patients, Associates With the Phenomenon of EMT
por: Zhang, Jia, et al.
Publicado: (2016)

Distinct patterns and prognostic values of tumor-infiltrating macrophages in hepatocellular carcinoma and gastric cancer
por: Li, Jin-Qing, et al.
Publicado: (2017)

ERR-activated GPR35 promotes immune infiltration level of macrophages in gastric cancer tissues
por: Shu, Chuanjun, et al.
Publicado: (2022)

The olive DGAT2 gene is developmentally regulated and shares overlapping but distinct expression patterns with DGAT1
por: Banilas, Georgios, et al.
Publicado: (2011)

Tumor-Infiltrating Lymphocytes and Cancer Markers in Osteosarcoma: Influence on Patient Survival
por: Casanova, José Manuel, et al.
Publicado: (2021)

M1(hot) tumor-associated macrophages boost tissue-resident memory T cells infiltration and survival in human lung cancer
por: Garrido-Martin, Eva M, et al.
Publicado: (2020)

DGAT1 protects tumor from lipotoxicity, emerging as a promising metabolic target for cancer therapy
por: Cheng, Xiang, et al.
Publicado: (2020)

Paclitaxel Promotes Tumor-Infiltrating Macrophages in Breast Cancer
por: Shen, Jun, et al.
Publicado: (2020)

Gastric Cancer Tumor Microenvironment Characterization Reveals Stromal-Related Gene Signatures Associated With Macrophage Infiltration
por: Wei, Shenyu, et al.
Publicado: (2020)

SLC2A3 promotes macrophage infiltration by glycolysis reprogramming in gastric cancer
por: Yao, Xingxing, et al.
Publicado: (2020)

Hepatic VLDL secretion: DGAT1 determines particle size but not particle number, which can be supported entirely by DGAT2
por: Irshad, Zehra, et al.
Publicado: (2019)

Helios Expression in Tumor-Infiltrating Lymphocytes Correlates with Overall Survival of Advanced Gastric Cancer Patients
por: Chen, Wei-Ming, et al.
Publicado: (2020)

Tumor-Infiltrating Immune Cells Are Associated With Prognosis of Gastric Cancer
por: Liu, Kai, et al.
Publicado: (2015)

Comprehensive Genetic Analysis of DGAT2 Mutations and Gene Expression Patterns in Human Cancers
por: Graber, Meghan, et al.
Publicado: (2021)

Prognostic value of tumor-infiltrating CD163(+)macrophage in patients with metastatic gastric cancer undergoing multidisciplinary treatment
por: Kinoshita, Jun, et al.
Publicado: (2022)

T‐cells infiltration mediates the association between neutrophil/lymphocyte ratio and survival in gastric cancer
por: He, Qifei, et al.
Publicado: (2023)

Macrophage Infiltration Induces Gastric Cancer Invasiveness by Activating the β-Catenin Pathway
por: Wu, Ming-Hsun, et al.
Publicado: (2015)

Transmembrane Protein 68 Functions as an MGAT and DGAT Enzyme for Triacylglycerol Biosynthesis
por: Wang, Yu, et al.
Publicado: (2023)

Tumor-infiltrating macrophages, cancer stem cells and therapeutic responses
por: Panni, Roheena Z., et al.
Publicado: (2012)

Phosphorylation and function of DGAT1 in skeletal muscle cells
por: Yu, Jinhai, et al.
Publicado: (2015)

Functional analysis of alternative castor bean DGAT enzymes
por: Trenz, Thomaz Stumpf, et al.
Publicado: (2022)

Overexpression of DGAT2 Regulates the Differentiation of Bovine Preadipocytes
por: Guo, Pan-Pan, et al.
Publicado: (2023)

Association of tumor deposits with tumor-infiltrating lymphocytes and prognosis in gastric cancer
por: Li, Xinyue, et al.
Publicado: (2022)

Genome-wide identification of Diacylglycerol Acyltransferases (DGAT) family genes influencing Milk production in Buffalo
por: Liu, Jiajia, et al.
Publicado: (2020)

Tumor‐infiltrating M2 macrophage in pretreatment biopsy sample predicts response to chemotherapy and survival in esophageal cancer
por: Yamamoto, Kei, et al.
Publicado: (2020)

Scoring System for Tumor-Infiltrating Lymphocytes and Its Prognostic Value for Gastric Cancer
por: Zhang, Dachuan, et al.
Publicado: (2019)

Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice
por: Streeper, Ryan S., et al.
Publicado: (2012)

Hypoxia Correlates With Poor Survival and M2 Macrophage Infiltration in Colorectal Cancer
por: Qi, Lina, et al.
Publicado: (2020)

Serine protease PRSS23 drives gastric cancer by enhancing tumor associated macrophage infiltration via FGF2
por: Qin, Shanshan, et al.
Publicado: (2022)

Tumor-infiltrating CD4(+) T cells in patients with gastric cancer
por: Yuan, Long, et al.
Publicado: (2017)

Overexpression of Type 1 and 2 Diacylglycerol Acyltransferase Genes (JcDGAT1 and JcDGAT2) Enhances Oil Production in the Woody Perennial Biofuel Plant Jatropha curcas
por: Zhang, Tian-Tian, et al.
Publicado: (2021)

Analysis of DGAT2 mutations reveals potential links between cancer and lipid droplet deregulation
por: Graber, Meghan, et al.
Publicado: (2021)

Identification of Potential Prognostic Biomarkers Associated With Macrophage M2 Infiltration in Gastric Cancer
por: Liu, Baohong, et al.
Publicado: (2022)

Identification of Differentially Expressed Genes Reveals BGN Predicting Overall Survival and Tumor Immune Infiltration of Gastric Cancer
por: Chen, Weizhi, et al.
Publicado: (2021)

BnDGAT1s Function Similarly in Oil Deposition and Are Expressed with Uniform Patterns in Tissues of Brassica napus
por: Zhao, Cuizhu, et al.
Publicado: (2017)

Tissue Expression and Variation of the DGAT2 Gene and Its Effect on Carcass and Meat Quality Traits in Yak
por: Hu, Jiang, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_r7eiv9cjhq261eqto75oarnto1