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Human menstrual blood-derived stem cells as immunoregulatory therapy in COVID-19: A case report and review of the literature
BACKGROUND: The coronavirus disease 2019 (COVID-19) caused by novel coronavirus 2019 in December 2019 has spread all around the globe and has caused a pandemic. There is still no current effective guidance on the clinical management of COVID-19. Mesenchymal stem cell therapy has been shown to be one...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7942055/ https://www.ncbi.nlm.nih.gov/pubmed/33728315 http://dx.doi.org/10.12998/wjcc.v9.i7.1705 |
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author | Lu, Juan Xie, Zhong-Yang Zhu, Dan-Hua Li, Lan-Juan |
author_facet | Lu, Juan Xie, Zhong-Yang Zhu, Dan-Hua Li, Lan-Juan |
author_sort | Lu, Juan |
collection | PubMed |
description | BACKGROUND: The coronavirus disease 2019 (COVID-19) caused by novel coronavirus 2019 in December 2019 has spread all around the globe and has caused a pandemic. There is still no current effective guidance on the clinical management of COVID-19. Mesenchymal stem cell therapy has been shown to be one of the therapeutic approaches to alleviate pneumonia and symptoms through their immunomo-dulatory effect in COVID-19 patients. CASE SUMMARY: We describe the first confirmed case of COVID-19 in Hangzhou to explore the role of human menstrual blood-derived stem cells (MenSCs) in the treatment of COVID-19. Moreover, we review the immunomodulation effect including non-specific and specific immune functions of MenSCs for the therapy of COVID-19. CONCLUSION: MenSCs can be helpful to find a promising therapeutic approach for COVID-19. |
format | Online Article Text |
id | pubmed-7942055 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-79420552021-03-15 Human menstrual blood-derived stem cells as immunoregulatory therapy in COVID-19: A case report and review of the literature Lu, Juan Xie, Zhong-Yang Zhu, Dan-Hua Li, Lan-Juan World J Clin Cases Case Report BACKGROUND: The coronavirus disease 2019 (COVID-19) caused by novel coronavirus 2019 in December 2019 has spread all around the globe and has caused a pandemic. There is still no current effective guidance on the clinical management of COVID-19. Mesenchymal stem cell therapy has been shown to be one of the therapeutic approaches to alleviate pneumonia and symptoms through their immunomo-dulatory effect in COVID-19 patients. CASE SUMMARY: We describe the first confirmed case of COVID-19 in Hangzhou to explore the role of human menstrual blood-derived stem cells (MenSCs) in the treatment of COVID-19. Moreover, we review the immunomodulation effect including non-specific and specific immune functions of MenSCs for the therapy of COVID-19. CONCLUSION: MenSCs can be helpful to find a promising therapeutic approach for COVID-19. Baishideng Publishing Group Inc 2021-03-06 2021-03-06 /pmc/articles/PMC7942055/ /pubmed/33728315 http://dx.doi.org/10.12998/wjcc.v9.i7.1705 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. |
spellingShingle | Case Report Lu, Juan Xie, Zhong-Yang Zhu, Dan-Hua Li, Lan-Juan Human menstrual blood-derived stem cells as immunoregulatory therapy in COVID-19: A case report and review of the literature |
title | Human menstrual blood-derived stem cells as immunoregulatory therapy in COVID-19: A case report and review of the literature |
title_full | Human menstrual blood-derived stem cells as immunoregulatory therapy in COVID-19: A case report and review of the literature |
title_fullStr | Human menstrual blood-derived stem cells as immunoregulatory therapy in COVID-19: A case report and review of the literature |
title_full_unstemmed | Human menstrual blood-derived stem cells as immunoregulatory therapy in COVID-19: A case report and review of the literature |
title_short | Human menstrual blood-derived stem cells as immunoregulatory therapy in COVID-19: A case report and review of the literature |
title_sort | human menstrual blood-derived stem cells as immunoregulatory therapy in covid-19: a case report and review of the literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7942055/ https://www.ncbi.nlm.nih.gov/pubmed/33728315 http://dx.doi.org/10.12998/wjcc.v9.i7.1705 |
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