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Optical coherence tomography findings in toxoplasma retinochoroiditis

PURPOSE: This study aimed to evaluate the optic coherence tomography (OCT) findings in patients with toxoplasmic retinochoroiditis (TRC). METHODS: A total of 12 eyes of 12 patients with active TRC were included in the study. At baseline, at the first-month follow-up, at the sixth-month follow-up and...

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Autores principales: Adıyeke, Seda Karaca, Uzakgider, Neslisah Kutlu, Doğan, Sıla, Aytogan, Hasan, Aras, Buket, Ture, Gamze, Talay, Ekrem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7942119/
https://www.ncbi.nlm.nih.gov/pubmed/33595490
http://dx.doi.org/10.4103/ijo.IJO_1061_20
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author Adıyeke, Seda Karaca
Uzakgider, Neslisah Kutlu
Doğan, Sıla
Aytogan, Hasan
Aras, Buket
Ture, Gamze
Talay, Ekrem
author_facet Adıyeke, Seda Karaca
Uzakgider, Neslisah Kutlu
Doğan, Sıla
Aytogan, Hasan
Aras, Buket
Ture, Gamze
Talay, Ekrem
author_sort Adıyeke, Seda Karaca
collection PubMed
description PURPOSE: This study aimed to evaluate the optic coherence tomography (OCT) findings in patients with toxoplasmic retinochoroiditis (TRC). METHODS: A total of 12 eyes of 12 patients with active TRC were included in the study. At baseline, at the first-month follow-up, at the sixth-month follow-up and at the 1-year follow-up, the TRC lesion OCT and macula OCT were evaluated. RESULTS: Hyperreflectivity of the inner retinal layers and an increase in retinal thickness were observed on the OCT examinations of all the patients with an active TRC lesion. The retinal thickness decreased and the reflectivity of retinal layers was disorganized in the OCT images obtained in the follow-up period. Partial posterior hyaloid detachment (PHD) and no PHD were detected in 11 cases and 1 case, respectively. Epiretinal membrane (ERM) had developed in the adjacent region of the scar in 7 patients. With the regression of the lesion, the disruption of the ellipsoid zone (EZ), retinal pigment epithelium (RPE) and external limiting membrane (ELM) improved in the adjacent areas. In all the eyes, ERM and the PHD configuration did progress during the follow-up period. Vitreoschisis was found in 4 of the 11 patients with partial PHD. It was observed that ERM developed in all the patients with vitreoschisis. CONCLUSION: ERM and partial PHD were common in the TRC patients, and there was no progression during the follow-up period. Regeneration of the EZ, RPE and ELM was observed in the follow-up period.
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spelling pubmed-79421192021-03-10 Optical coherence tomography findings in toxoplasma retinochoroiditis Adıyeke, Seda Karaca Uzakgider, Neslisah Kutlu Doğan, Sıla Aytogan, Hasan Aras, Buket Ture, Gamze Talay, Ekrem Indian J Ophthalmol Special Focus on Ocular Inflammation, Original Article PURPOSE: This study aimed to evaluate the optic coherence tomography (OCT) findings in patients with toxoplasmic retinochoroiditis (TRC). METHODS: A total of 12 eyes of 12 patients with active TRC were included in the study. At baseline, at the first-month follow-up, at the sixth-month follow-up and at the 1-year follow-up, the TRC lesion OCT and macula OCT were evaluated. RESULTS: Hyperreflectivity of the inner retinal layers and an increase in retinal thickness were observed on the OCT examinations of all the patients with an active TRC lesion. The retinal thickness decreased and the reflectivity of retinal layers was disorganized in the OCT images obtained in the follow-up period. Partial posterior hyaloid detachment (PHD) and no PHD were detected in 11 cases and 1 case, respectively. Epiretinal membrane (ERM) had developed in the adjacent region of the scar in 7 patients. With the regression of the lesion, the disruption of the ellipsoid zone (EZ), retinal pigment epithelium (RPE) and external limiting membrane (ELM) improved in the adjacent areas. In all the eyes, ERM and the PHD configuration did progress during the follow-up period. Vitreoschisis was found in 4 of the 11 patients with partial PHD. It was observed that ERM developed in all the patients with vitreoschisis. CONCLUSION: ERM and partial PHD were common in the TRC patients, and there was no progression during the follow-up period. Regeneration of the EZ, RPE and ELM was observed in the follow-up period. Wolters Kluwer - Medknow 2021-03 2021-02-17 /pmc/articles/PMC7942119/ /pubmed/33595490 http://dx.doi.org/10.4103/ijo.IJO_1061_20 Text en Copyright: © 2021 Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Special Focus on Ocular Inflammation, Original Article
Adıyeke, Seda Karaca
Uzakgider, Neslisah Kutlu
Doğan, Sıla
Aytogan, Hasan
Aras, Buket
Ture, Gamze
Talay, Ekrem
Optical coherence tomography findings in toxoplasma retinochoroiditis
title Optical coherence tomography findings in toxoplasma retinochoroiditis
title_full Optical coherence tomography findings in toxoplasma retinochoroiditis
title_fullStr Optical coherence tomography findings in toxoplasma retinochoroiditis
title_full_unstemmed Optical coherence tomography findings in toxoplasma retinochoroiditis
title_short Optical coherence tomography findings in toxoplasma retinochoroiditis
title_sort optical coherence tomography findings in toxoplasma retinochoroiditis
topic Special Focus on Ocular Inflammation, Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7942119/
https://www.ncbi.nlm.nih.gov/pubmed/33595490
http://dx.doi.org/10.4103/ijo.IJO_1061_20
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