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Genome-wide analysis of DNA methylation in Hirschsprung enteric precursor cells: unraveling the epigenetic landscape of enteric nervous system development
BACKGROUND: Hirschsprung disease (HSCR, OMIM 142623) is a rare congenital disorder that results from a failure to fully colonize the gut by enteric precursor cells (EPCs) derived from the neural crest. Such incomplete gut colonization is due to alterations in EPCs proliferation, survival, migration...
Autores principales: | Villalba-Benito, Leticia, López-López, Daniel, Torroglosa, Ana, Casimiro-Soriguer, Carlos S., Luzón-Toro, Berta, Fernández, Raquel María, Moya-Jiménez, María José, Antiñolo, Guillermo, Dopazo, Joaquín, Borrego, Salud |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7942176/ https://www.ncbi.nlm.nih.gov/pubmed/33750457 http://dx.doi.org/10.1186/s13148-021-01040-6 |
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