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Nicotine upregulates ACE2 expression and increases competence for SARS-CoV-2 in human pneumocytes

The coronavirus disease 2019 (COVID-19) pandemic has a variable degree of severity according to underlying comorbidities and life-style. Several research groups have reported an association between cigarette smoking and increased severity of COVID-19. The exact mechanism of action is largely unclear...

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Detalles Bibliográficos
Autores principales: Maggi, Fabrizio, Rosellini, Alfredo, Spezia, Pietro Giorgio, Focosi, Daniele, Macera, Lisa, Lai, Michele, Pistello, Mauro, de Iure, Antonio, Tomino, Carlo, Bonassi, Stefano, Russo, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7942220/
https://www.ncbi.nlm.nih.gov/pubmed/33850935
http://dx.doi.org/10.1183/23120541.00713-2020