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Targeting the IDO-BCL2A1-Cytochrome c Pathway Promotes Apoptosis in Oral Squamous Cell Carcinoma

PURPOSE: Indolamine 2,3-dioxygenase (IDO) is the rate limiting enzyme of tryptophan degradation and is a negative prognostic factor in oral squamous cell carcinoma (OSCC) patients, while the underlying molecular mechanism remains unclear. This research aimed to explore the IDO expression and its bio...

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Detalles Bibliográficos
Autores principales: Zheng, Qiaoping, Gan, Guifang, Gao, Xianfu, Luo, Qingqiong, Chen, Fuxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7942955/
https://www.ncbi.nlm.nih.gov/pubmed/33707952
http://dx.doi.org/10.2147/OTT.S288692