Cargando…

Targeting the IDO-BCL2A1-Cytochrome c Pathway Promotes Apoptosis in Oral Squamous Cell Carcinoma

PURPOSE: Indolamine 2,3-dioxygenase (IDO) is the rate limiting enzyme of tryptophan degradation and is a negative prognostic factor in oral squamous cell carcinoma (OSCC) patients, while the underlying molecular mechanism remains unclear. This research aimed to explore the IDO expression and its bio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Qiaoping, Gan, Guifang, Gao, Xianfu, Luo, Qingqiong, Chen, Fuxiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7942955/ https://www.ncbi.nlm.nih.gov/pubmed/33707952 http://dx.doi.org/10.2147/OTT.S288692

Ejemplares similares

PPT1 Reduction Contributes to Erianin-Induced Growth Inhibition in Oral Squamous Carcinoma Cells
por: Luo, Qingqiong, et al.
Publicado: (2021)

Role of toll-like receptor 4 on the immune escape of human oral squamous cell carcinoma and resistance of cisplatin-induced apoptosis
por: Sun, Zujun, et al.
Publicado: (2012)

NLRP3 promotes tumor growth and metastasis in human oral squamous cell carcinoma
por: Wang, Han, et al.
Publicado: (2018)

Zymosan promotes proliferation, Candida albicans adhesion and IL-1β production of oral squamous cell carcinoma in vitro
por: Chen, Xu, et al.
Publicado: (2020)

Overexpression of SENP3 in oral squamous cell carcinoma and its association with differentiation
por: SUN, ZUJUN, et al.
Publicado: (2013)

Bitter melon derived extracellular vesicles enhance the therapeutic effects and reduce the drug resistance of 5-fluorouracil on oral squamous cell carcinoma
por: Yang, Meng, et al.
Publicado: (2021)

The role of NLRP3 inflammasome in 5-fluorouracil resistance of oral squamous cell carcinoma
por: Feng, Xiaodong, et al.
Publicado: (2017)

In vitro and in vivo anti-tumor effect of metformin as a novel therapeutic agent in human oral squamous cell carcinoma
por: Luo, Qingqiong, et al.
Publicado: (2012)

Serum Response Factor-Regulated IDO1/Kyn-Ahr Pathway Promotes Tumorigenesis of Oral Squamous Cell Carcinoma
por: Xu, Mingyan, et al.
Publicado: (2023)

Kynurenine catabolic enzyme KMO regulates HCC growth
por: Shi, Zhaopeng, et al.
Publicado: (2022)

Activation of Bcl-2-Caspase-9 Apoptosis Pathway in the Testis of Asthmatic Mice
por: Xu, Wenyuan, et al.
Publicado: (2016)

IDO1 is highly expressed in macrophages of patients in advanced tumour stages of oral squamous cell carcinoma
por: Struckmeier, Ann-Kristin, et al.
Publicado: (2022)

The Pharmacological NF-κB Inhibitor BAY11-7082 Induces Cell Apoptosis and Inhibits the Migration of Human Uveal Melanoma Cells
por: Hu, Shuiqing, et al.
Publicado: (2012)

Proliferation and Apoptosis Pathways and Factors in Oral Squamous Cell Carcinoma
por: He, Steven, et al.
Publicado: (2022)

Tubeimoside-1 induces glioma apoptosis through regulation of Bax/Bcl-2 and the ROS/Cytochrome C/Caspase-3 pathway
por: Jia, Geng, et al.
Publicado: (2015)

An efficient method to isolate lemon derived extracellular vesicles for gastric cancer therapy
por: Yang, Meng, et al.
Publicado: (2020)

The BCL-2 family protein BCL-RAMBO interacts and cooperates with GRP75 to promote its apoptosis signaling pathway
por: Xu, Jinghong, et al.
Publicado: (2023)

BCL11A Promotes the Progression of Laryngeal Squamous Cell Carcinoma
por: Zhou, Jian, et al.
Publicado: (2020)

Exploitation of the IDO Pathway in the Therapy of Rheumatoid Arthritis
por: Williams, Richard O.
Publicado: (2013)

Long noncoding RNA CEBPA-DT promotes cisplatin chemo-resistance through CEBPA/BCL2 mediated apoptosis in oral squamous cellular cancer
por: Qiao, Xue, et al.
Publicado: (2021)

Hypoxia induced Bcl-2/Twist1 complex promotes tumor cell invasion in oral squamous cell carcinoma
por: Duan, Yuansheng, et al.
Publicado: (2016)

Assessment of Bax and Bcl-2 Immunoexpression in Patients with Oral Lichen Planus and Oral Squamous Cell Carcinoma
por: Nafarzadeh, Shima, et al.
Publicado: (2013)

P53 and bcl-2 immunoexpression in patients with oral lichen planus and oral squamous cell carcinoma
por: Leyva-Huerta, Elba R., et al.
Publicado: (2012)

Silibinin Triggers the Mitochondrial Pathway of Apoptosis in Human Oral Squamous Carcinoma Cells
por: Iyengar, Radhika Murali, et al.
Publicado: (2020)

PKM2 regulates proliferation and apoptosis through the Hippo pathway in oral tongue squamous cell carcinoma
por: Luo, Jia, et al.
Publicado: (2021)

Translational control of Bcl-2 promotes apoptosis of gastric carcinoma cells
por: Tao, Shuangfen, et al.
Publicado: (2021)

Protective effect of galangin in Concanavalin A-induced hepatitis in mice
por: Luo, Qingqiong, et al.
Publicado: (2015)

Antimicrobial Resistance and Molecular Characteristics of Nasal Staphylococcus aureus Isolates From Newly Admitted Inpatients
por: Chen, Xu, et al.
Publicado: (2016)

Eugenol Induces Apoptosis in Tongue Squamous Carcinoma Cells by Mediating the Expression of Bcl-2 Family
por: Surducan, Dan-Alexandru, et al.
Publicado: (2022)

Garlic ((Allium sativum)) Fresh Juice Induces Apoptosis in Human Oral Squamous Cell Carcinoma: The Involvement of Caspase-3, Bax and Bcl-2
por: Farhadi, Farrokh, et al.
Publicado: (2015)

IDO/kynurenine pathway in cancer: possible therapeutic approaches
por: Abd El-Fattah, Eslam E.
Publicado: (2022)

Bcl-2–regulated apoptosis and cytochrome c release can occur independently of both caspase-2 and caspase-9
por: Marsden, Vanessa S., et al.
Publicado: (2004)

Vitamin C Promotes Apoptosis and Cell Cycle Arrest in Oral Squamous Cell Carcinoma
por: Zhou, Jianjun, et al.
Publicado: (2020)

As a Novel Tumor Suppressor, LHPP Promotes Apoptosis by Inhibiting the PI3K/AKT Signaling Pathway in Oral Squamous Cell Carcinoma
por: Liu, Shanshan, et al.
Publicado: (2022)

Impact of IDO1 and IDO2 on the B Cell Immune Response
por: Merlo, Lauren M. F., et al.
Publicado: (2022)

BCL-2 inhibition impairs mitochondrial function and targets oral tongue squamous cell carcinoma
por: Xiong, Lei, et al.
Publicado: (2016)

Overexpression of miR-155 promotes the proliferation and invasion of oral squamous carcinoma cells by regulating BCL6/cyclin D2
por: ZENG, QI, et al.
Publicado: (2016)

Circulating Antibodies to IDO/THO Pathway Metabolites in Alzheimer's Disease
por: Duleu, S., et al.
Publicado: (2010)

Targeting the IDO1 pathway in cancer: from bench to bedside
por: Liu, Ming, et al.
Publicado: (2018)

Syringic acid induces apoptosis in human oral squamous carcinoma cells through mitochondrial pathway
por: Abijeth, Bhaskhar, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_i6sbesbq59ddca83j9qdhddu3d