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EZH2 inhibition decreases neuroblastoma proliferation and in vivo tumor growth

Investigation of the mechanisms responsible for aggressive neuroblastoma and its poor prognosis is critical to identify novel therapeutic targets and improve survival. Enhancer of Zeste Homolog 2 (EZH2) is known to play a key role in supporting the malignant phenotype in several cancer types and kno...

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Detalles Bibliográficos
Autores principales: Bownes, Laura V., Williams, Adele P., Marayati, Raoud, Stafman, Laura L., Markert, Hooper, Quinn, Colin H., Wadhwani, Nikita, Aye, Jamie M., Stewart, Jerry E., Yoon, Karina J., Mroczek-Musulman, Elizabeth, Beierle, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7942994/
https://www.ncbi.nlm.nih.gov/pubmed/33690617
http://dx.doi.org/10.1371/journal.pone.0246244