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EZH2 inhibition decreases neuroblastoma proliferation and in vivo tumor growth
Investigation of the mechanisms responsible for aggressive neuroblastoma and its poor prognosis is critical to identify novel therapeutic targets and improve survival. Enhancer of Zeste Homolog 2 (EZH2) is known to play a key role in supporting the malignant phenotype in several cancer types and kno...
Autores principales: | Bownes, Laura V., Williams, Adele P., Marayati, Raoud, Stafman, Laura L., Markert, Hooper, Quinn, Colin H., Wadhwani, Nikita, Aye, Jamie M., Stewart, Jerry E., Yoon, Karina J., Mroczek-Musulman, Elizabeth, Beierle, Elizabeth A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7942994/ https://www.ncbi.nlm.nih.gov/pubmed/33690617 http://dx.doi.org/10.1371/journal.pone.0246244 |
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