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Selective inhibition of V600E-mutant BRAF gene induces apoptosis in thyroid carcinoma cell lines

PURPOSE: Papillary thyroid cancer (PTC) has a high incidence of BRAF(V600E) mutation. The purpose of this study was to evaluate the potential relationship between thyroiditis and BRAF(V600E) mutation status in patients with PTC. We investigated how a selective inhibitor of BRAF(V600E) PLX4032 affect...

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Detalles Bibliográficos
Autores principales:	Park, Kyoung Sik, Saindane, Madhuri, Yang, Eun Yeol, Jin, TongYi, Rallabandi, Harikrishna Reddy, Heil, Alexander, Nam, Sang Eun, Yoo, Young Bum, Yang, Jung-Hyun, Kim, Jong Bin, Park, Seo-Young, Park, Won Seo, Youn, Yeo-Kyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Surgical Society 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943282/ https://www.ncbi.nlm.nih.gov/pubmed/33748026 http://dx.doi.org/10.4174/astr.2021.100.3.127

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