Toxic Anterior Segment Syndrome with Intracameral Moxifloxacin: Case Report and Review of the Literature

A case of severe anterior segment toxicity secondary to high-volume, undiluted intracameral moxifloxacin for endophthalmitis prophylaxis is reported. We examine the other reported cases of toxicity after intracameral moxifloxacin, as well as iris depigmentation and transillumination syndromes after...

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Detalles Bibliográficos
Autores principales: Amireskandari, Annahita, Bean, Andrew, Mauger, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943300/
https://www.ncbi.nlm.nih.gov/pubmed/33747588
http://dx.doi.org/10.1155/2021/5526097
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author Amireskandari, Annahita
Bean, Andrew
Mauger, Thomas
author_facet Amireskandari, Annahita
Bean, Andrew
Mauger, Thomas
author_sort Amireskandari, Annahita
collection PubMed
description A case of severe anterior segment toxicity secondary to high-volume, undiluted intracameral moxifloxacin for endophthalmitis prophylaxis is reported. We examine the other reported cases of toxicity after intracameral moxifloxacin, as well as iris depigmentation and transillumination syndromes after oral and topical fluoroquinolone exposure. Additionally, we review the literature on safety, efficacy, and appropriate dosing of intracameral antibiotics with a focus on moxifloxacin.
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spelling pubmed-79433002021-03-18 Toxic Anterior Segment Syndrome with Intracameral Moxifloxacin: Case Report and Review of the Literature Amireskandari, Annahita Bean, Andrew Mauger, Thomas Case Rep Ophthalmol Med Case Report A case of severe anterior segment toxicity secondary to high-volume, undiluted intracameral moxifloxacin for endophthalmitis prophylaxis is reported. We examine the other reported cases of toxicity after intracameral moxifloxacin, as well as iris depigmentation and transillumination syndromes after oral and topical fluoroquinolone exposure. Additionally, we review the literature on safety, efficacy, and appropriate dosing of intracameral antibiotics with a focus on moxifloxacin. Hindawi 2021-03-02 /pmc/articles/PMC7943300/ /pubmed/33747588 http://dx.doi.org/10.1155/2021/5526097 Text en Copyright © 2021 Annahita Amireskandari et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Amireskandari, Annahita
Bean, Andrew
Mauger, Thomas
Toxic Anterior Segment Syndrome with Intracameral Moxifloxacin: Case Report and Review of the Literature
title Toxic Anterior Segment Syndrome with Intracameral Moxifloxacin: Case Report and Review of the Literature
title_full Toxic Anterior Segment Syndrome with Intracameral Moxifloxacin: Case Report and Review of the Literature
title_fullStr Toxic Anterior Segment Syndrome with Intracameral Moxifloxacin: Case Report and Review of the Literature
title_full_unstemmed Toxic Anterior Segment Syndrome with Intracameral Moxifloxacin: Case Report and Review of the Literature
title_short Toxic Anterior Segment Syndrome with Intracameral Moxifloxacin: Case Report and Review of the Literature
title_sort toxic anterior segment syndrome with intracameral moxifloxacin: case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943300/
https://www.ncbi.nlm.nih.gov/pubmed/33747588
http://dx.doi.org/10.1155/2021/5526097
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