Cargando…

Unraveling the Molecular Nexus between GPCRs, ERS, and EMT

G protein-coupled receptors (GPCRs) represent a large family of transmembrane proteins that transduce an external stimulus into a variety of cellular responses. They play a critical role in various pathological conditions in humans, including cancer, by regulating a number of key processes involved...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kumari, Niti, Reabroi, Somrudee, North, Brian J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943314/ https://www.ncbi.nlm.nih.gov/pubmed/33746610 http://dx.doi.org/10.1155/2021/6655417

Ejemplares similares

Andrographolide Exhibits Anticancer Activity against Breast Cancer Cells (MCF-7 and MDA-MB-231 Cells) through Suppressing Cell Proliferation and Inducing Cell Apoptosis via Inactivation of ER-α Receptor and PI3K/AKT/mTOR Signaling
por: Tohkayomatee, Ruhainee, et al.
Publicado: (2022)

Gambogic Acid Inhibits Wnt/β-catenin Signaling and Induces ER Stress-Mediated Apoptosis in Human Cholangiocarcinoma
por: Suksen, Kanoknetr, et al.
Publicado: (2021)

Plumbagin Suppresses Breast Cancer Progression by Downregulating HIF-1α Expression via a PI3K/Akt/mTOR Independent Pathway under Hypoxic Condition
por: Jampasri, Supawan, et al.
Publicado: (2022)

Molecular Approaches To Target GPCRs in Cancer Therapy
por: Innamorati, Giulio, et al.
Publicado: (2011)

Cracking the elusive alignment hypothesis: the microtubule–cellulose synthase nexus unraveled
por: Bringmann, Martin, et al.
Publicado: (2012)

Illuminating the life of GPCRs
por: Böhme, Ilka, et al.
Publicado: (2009)

The GTPase Rab43 Controls the Anterograde ER-Golgi Trafficking and Sorting of GPCRs
por: Li, Chunman, et al.
Publicado: (2017)

How Do Molecular Dynamics Data Complement Static Structural Data of GPCRs
por: Torrens-Fontanals, Mariona, et al.
Publicado: (2020)

Unraveling the Molecular Puzzle: Exploring Gene Networks across Diverse EMT Status of Cell Lines
por: Park, Heewon
Publicado: (2023)

Using GPCRs as Molecular Beacons to Target Ovarian Cancer with Nanomedicines
por: Khetan, Riya, et al.
Publicado: (2022)

Molecular basis of signaling specificity between GIRK channels and GPCRs
por: Touhara, Kouki K, et al.
Publicado: (2018)

Unraveling the Nexus: Exploring the Relationship between Exercise Habits and Sleep Quality in Older Adults
por: Xu, Wenhu, et al.
Publicado: (2023)

Less Exploited GPCRs in Precision Medicine: Targets for Molecular Imaging and Theranostics
por: Franco Machado, João, et al.
Publicado: (2018)

Proton-Sensing GPCRs in Health and Disease
por: Sisignano, Marco, et al.
Publicado: (2021)

High-mass MALDI-MS unravels ligand-mediated G protein–coupling selectivity to GPCRs
por: Wu, Na, et al.
Publicado: (2021)

Editorial: Molecular modulators of GPCRs signal transduction
por: Vrecl, Milka, et al.
Publicado: (2023)

The anti-cancer activity of an andrographolide analogue functions through a GSK-3β-independent Wnt/β-catenin signaling pathway in colorectal cancer cells
por: Reabroi, Somrudee, et al.
Publicado: (2018)

Novel Therapeutic GPCRs for Psychiatric Disorders
por: Komatsu, Hidetoshi
Publicado: (2015)

Ligands and Beyond: Mechanosensitive Adhesion GPCRs
por: Lin, Hsi-Hsien, et al.
Publicado: (2022)

Endogenous Anti-Cancer Candidates in GPCR, ER Stress, and EMT
por: Gundamaraju, Rohit, et al.
Publicado: (2020)

Specific TBC Domain-Containing Proteins Control the ER-Golgi-Plasma Membrane Trafficking of GPCRs
por: Wei, Zhe, et al.
Publicado: (2019)

The Role of G Protein-Coupled Receptors (GPCRs) and Calcium Signaling in Schizophrenia. Focus on GPCRs Activated by Neurotransmitters and Chemokines
por: Boczek, Tomasz, et al.
Publicado: (2021)

Action of Molecular Switches in GPCRs - Theoretical and Experimental Studies
por: Trzaskowski, B, et al.
Publicado: (2012)

The role of GPCRs in bone diseases and dysfunctions
por: Luo, Jian, et al.
Publicado: (2019)

New Insights into the Structure and Function of Class B1 GPCRs
por: Cary, Brian P, et al.
Publicado: (2022)

Diabetes, Epstein-Barr virus and extranodal natural killer/T-cell lymphoma in India: Unravelling the plausible nexus
por: Spadigam, Anita, et al.
Publicado: (2016)

Physiological relevance of proton-activated GPCRs
por: Imenez Silva, Pedro H., et al.
Publicado: (2022)

Allosteric Modulation of GPCRs of Class A by Cholesterol
por: Jakubík, Jan, et al.
Publicado: (2021)

GPCRs: The most promiscuous druggable receptor of the mankind
por: Alhosaini, Khaled, et al.
Publicado: (2021)

Endomembrane-Based Signaling by GPCRs and G-Proteins
por: Liccardo, Federica, et al.
Publicado: (2022)

Role of G-Proteins and GPCRs in Cardiovascular Pathologies
por: Kaur, Geetika, et al.
Publicado: (2023)

The folding interactome of GPCRs
por: Bergmayr, Christian, et al.
Publicado: (2011)

Neuropeptide GPCRs in Neuroendocrinology
por: Vaudry, Hubert, et al.
Publicado: (2014)

Editorial: GPCRs and Cancer
por: Chen, Suzie
Publicado: (2017)

An Overview on GPCRs and Drug Discovery: Structure-Based Drug Design and Structural Biology on GPCRs
por: Lundstrom, Kenneth
Publicado: (2009)

Drosophila Gut—A Nexus Between Dietary Restriction and Lifespan
por: Lian, Ting, et al.
Publicado: (2018)

The Origin of GPCRs: Identification of Mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in Fungi
por: Krishnan, Arunkumar, et al.
Publicado: (2012)

Metabolite-sensing GPCRs controlling interactions between adipose tissue and inflammation
por: Duncan, Elaine M., et al.
Publicado: (2023)

G Protein-Coupled Receptors (GPCRs)-Mediated Calcium Signaling in Ovarian Cancer: Focus on GPCRs activated by Neurotransmitters and Inflammation-Associated Molecules
por: Predescu, Dragoș-Valentin, et al.
Publicado: (2019)

Nexus between COVID-19 and periodontal disease
por: Sukumar, Kanchana, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_sr2gcq192h7nrgud30acshhhg3