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An antibody-free LC-MS/MS method for the quantification of intact insulin-like growth factors 1 and 2 in human plasma

Insulin-like growth factors 1 and 2 (IGF-1 and IGF-2) are important biomarkers in research and diagnosis of growth disorders. Quantitative analysis is performed using various ligand-binding assays or enzymatic digestion LC-MS/MS methods, whose widespread adoption is hampered by time-consuming sample...

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Detalles Bibliográficos
Autores principales: Pratt, Mark S., van Faassen, Martijn, Remmelts, Noah, Bischoff, Rainer, Kema, Ido P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943504/
https://www.ncbi.nlm.nih.gov/pubmed/33569646
http://dx.doi.org/10.1007/s00216-021-03185-y