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The impact of contact tracing and household bubbles on deconfinement strategies for COVID-19

The COVID-19 pandemic caused many governments to impose policies restricting social interactions. A controlled and persistent release of lockdown measures covers many potential strategies and is subject to extensive scenario analyses. Here, we use an individual-based model (STRIDE) to simulate inter...

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Detalles Bibliográficos
Autores principales: Willem, Lander, Abrams, Steven, Libin, Pieter J. K., Coletti, Pietro, Kuylen, Elise, Petrof, Oana, Møgelmose, Signe, Wambua, James, Herzog, Sereina A., Faes, Christel, Beutels, Philippe, Hens, Niel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943552/
https://www.ncbi.nlm.nih.gov/pubmed/33750778
http://dx.doi.org/10.1038/s41467-021-21747-7
Descripción
Sumario:The COVID-19 pandemic caused many governments to impose policies restricting social interactions. A controlled and persistent release of lockdown measures covers many potential strategies and is subject to extensive scenario analyses. Here, we use an individual-based model (STRIDE) to simulate interactions between 11 million inhabitants of Belgium at different levels including extended household settings, i.e., “household bubbles”. The burden of COVID-19 is impacted by both the intensity and frequency of physical contacts, and therefore, household bubbles have the potential to reduce hospital admissions by 90%. In addition, we find that it is crucial to complete contact tracing 4 days after symptom onset. Assumptions on the susceptibility of children affect the impact of school reopening, though we find that business and leisure-related social mixing patterns have more impact on COVID-19 associated disease burden. An optimal deployment of the mitigation policies under study require timely compliance to physical distancing, testing and self-isolation.