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The impact of contact tracing and household bubbles on deconfinement strategies for COVID-19

The COVID-19 pandemic caused many governments to impose policies restricting social interactions. A controlled and persistent release of lockdown measures covers many potential strategies and is subject to extensive scenario analyses. Here, we use an individual-based model (STRIDE) to simulate inter...

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Autores principales: Willem, Lander, Abrams, Steven, Libin, Pieter J. K., Coletti, Pietro, Kuylen, Elise, Petrof, Oana, Møgelmose, Signe, Wambua, James, Herzog, Sereina A., Faes, Christel, Beutels, Philippe, Hens, Niel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943552/
https://www.ncbi.nlm.nih.gov/pubmed/33750778
http://dx.doi.org/10.1038/s41467-021-21747-7
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author Willem, Lander
Abrams, Steven
Libin, Pieter J. K.
Coletti, Pietro
Kuylen, Elise
Petrof, Oana
Møgelmose, Signe
Wambua, James
Herzog, Sereina A.
Faes, Christel
Beutels, Philippe
Hens, Niel
author_facet Willem, Lander
Abrams, Steven
Libin, Pieter J. K.
Coletti, Pietro
Kuylen, Elise
Petrof, Oana
Møgelmose, Signe
Wambua, James
Herzog, Sereina A.
Faes, Christel
Beutels, Philippe
Hens, Niel
author_sort Willem, Lander
collection PubMed
description The COVID-19 pandemic caused many governments to impose policies restricting social interactions. A controlled and persistent release of lockdown measures covers many potential strategies and is subject to extensive scenario analyses. Here, we use an individual-based model (STRIDE) to simulate interactions between 11 million inhabitants of Belgium at different levels including extended household settings, i.e., “household bubbles”. The burden of COVID-19 is impacted by both the intensity and frequency of physical contacts, and therefore, household bubbles have the potential to reduce hospital admissions by 90%. In addition, we find that it is crucial to complete contact tracing 4 days after symptom onset. Assumptions on the susceptibility of children affect the impact of school reopening, though we find that business and leisure-related social mixing patterns have more impact on COVID-19 associated disease burden. An optimal deployment of the mitigation policies under study require timely compliance to physical distancing, testing and self-isolation.
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spelling pubmed-79435522021-03-28 The impact of contact tracing and household bubbles on deconfinement strategies for COVID-19 Willem, Lander Abrams, Steven Libin, Pieter J. K. Coletti, Pietro Kuylen, Elise Petrof, Oana Møgelmose, Signe Wambua, James Herzog, Sereina A. Faes, Christel Beutels, Philippe Hens, Niel Nat Commun Article The COVID-19 pandemic caused many governments to impose policies restricting social interactions. A controlled and persistent release of lockdown measures covers many potential strategies and is subject to extensive scenario analyses. Here, we use an individual-based model (STRIDE) to simulate interactions between 11 million inhabitants of Belgium at different levels including extended household settings, i.e., “household bubbles”. The burden of COVID-19 is impacted by both the intensity and frequency of physical contacts, and therefore, household bubbles have the potential to reduce hospital admissions by 90%. In addition, we find that it is crucial to complete contact tracing 4 days after symptom onset. Assumptions on the susceptibility of children affect the impact of school reopening, though we find that business and leisure-related social mixing patterns have more impact on COVID-19 associated disease burden. An optimal deployment of the mitigation policies under study require timely compliance to physical distancing, testing and self-isolation. Nature Publishing Group UK 2021-03-09 /pmc/articles/PMC7943552/ /pubmed/33750778 http://dx.doi.org/10.1038/s41467-021-21747-7 Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Willem, Lander
Abrams, Steven
Libin, Pieter J. K.
Coletti, Pietro
Kuylen, Elise
Petrof, Oana
Møgelmose, Signe
Wambua, James
Herzog, Sereina A.
Faes, Christel
Beutels, Philippe
Hens, Niel
The impact of contact tracing and household bubbles on deconfinement strategies for COVID-19
title The impact of contact tracing and household bubbles on deconfinement strategies for COVID-19
title_full The impact of contact tracing and household bubbles on deconfinement strategies for COVID-19
title_fullStr The impact of contact tracing and household bubbles on deconfinement strategies for COVID-19
title_full_unstemmed The impact of contact tracing and household bubbles on deconfinement strategies for COVID-19
title_short The impact of contact tracing and household bubbles on deconfinement strategies for COVID-19
title_sort impact of contact tracing and household bubbles on deconfinement strategies for covid-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943552/
https://www.ncbi.nlm.nih.gov/pubmed/33750778
http://dx.doi.org/10.1038/s41467-021-21747-7
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