Cargando…
Lasso-grafting of macrocyclic peptide pharmacophores yields multi-functional proteins
Protein engineering has great potential for devising multifunctional recombinant proteins to serve as next-generation protein therapeutics, but it often requires drastic modifications of the parental protein scaffolds e.g., additional domains at the N/C-terminus or replacement of a domain by another...
| Autores principales: | , , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943567/ https://www.ncbi.nlm.nih.gov/pubmed/33750839 http://dx.doi.org/10.1038/s41467-021-21875-0 |