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Triple-Negative Breast Cancer: Intact Mismatch Repair and Partial Co-Expression of PD-L1 and LAG-3

BACKGROUND AND AIM: Poor response to immune checkpoint inhibitors (ICIs) has been observed in most triple-negative breast cancer (TNBC) cases (around 80%). Our aim was to investigate the status of mismatch repair (MMR), microsatellite instability (MSI), programmed death-ligand 1 (PD-L1), and lymphoc...

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Detalles Bibliográficos
Autores principales: Wu, Shafei, Shi, Xiaohua, Wang, Jing, Wang, Xuefei, Liu, Yuanyuan, Luo, Yufeng, Mao, Feng, Zeng, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943629/
https://www.ncbi.nlm.nih.gov/pubmed/33717059
http://dx.doi.org/10.3389/fimmu.2021.561793