Multiple Origins of Extracellular DNA Traps

Extracellular DNA traps (ETs) are evolutionarily conserved antimicrobial mechanisms present in protozoa, plants, and animals. In this review, we compare their similarities in species of different taxa, and put forward the hypothesis that ETs have multiple origins. Our results are consistent with a p...

Descripción completa

Detalles Bibliográficos
Autores principales: Ramos-Martínez, Edgar, Hernández-González, Leticia, Ramos-Martínez, Iván, Pérez-Campos Mayoral, Laura, López-Cortés, Georgina I., Pérez-Campos, Eduardo, Mayoral Andrade, Gabriel, Hernández-Huerta, María Teresa, José, Marco V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943724/
https://www.ncbi.nlm.nih.gov/pubmed/33717121
http://dx.doi.org/10.3389/fimmu.2021.621311
Descripción
Sumario:Extracellular DNA traps (ETs) are evolutionarily conserved antimicrobial mechanisms present in protozoa, plants, and animals. In this review, we compare their similarities in species of different taxa, and put forward the hypothesis that ETs have multiple origins. Our results are consistent with a process of evolutionary convergence in multicellular organisms through the application of a congruency test. Furthermore, we discuss why multicellularity is related to the presence of a mechanism initiating the formation of ETs.

Ejemplares similares