Multiple Origins of Extracellular DNA Traps

Extracellular DNA traps (ETs) are evolutionarily conserved antimicrobial mechanisms present in protozoa, plants, and animals. In this review, we compare their similarities in species of different taxa, and put forward the hypothesis that ETs have multiple origins. Our results are consistent with a p...

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Autores principales: Ramos-Martínez, Edgar, Hernández-González, Leticia, Ramos-Martínez, Iván, Pérez-Campos Mayoral, Laura, López-Cortés, Georgina I., Pérez-Campos, Eduardo, Mayoral Andrade, Gabriel, Hernández-Huerta, María Teresa, José, Marco V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943724/
https://www.ncbi.nlm.nih.gov/pubmed/33717121
http://dx.doi.org/10.3389/fimmu.2021.621311
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author Ramos-Martínez, Edgar
Hernández-González, Leticia
Ramos-Martínez, Iván
Pérez-Campos Mayoral, Laura
López-Cortés, Georgina I.
Pérez-Campos, Eduardo
Mayoral Andrade, Gabriel
Hernández-Huerta, María Teresa
José, Marco V.
author_facet Ramos-Martínez, Edgar
Hernández-González, Leticia
Ramos-Martínez, Iván
Pérez-Campos Mayoral, Laura
López-Cortés, Georgina I.
Pérez-Campos, Eduardo
Mayoral Andrade, Gabriel
Hernández-Huerta, María Teresa
José, Marco V.
author_sort Ramos-Martínez, Edgar
collection PubMed
description Extracellular DNA traps (ETs) are evolutionarily conserved antimicrobial mechanisms present in protozoa, plants, and animals. In this review, we compare their similarities in species of different taxa, and put forward the hypothesis that ETs have multiple origins. Our results are consistent with a process of evolutionary convergence in multicellular organisms through the application of a congruency test. Furthermore, we discuss why multicellularity is related to the presence of a mechanism initiating the formation of ETs.
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spelling pubmed-79437242021-03-11 Multiple Origins of Extracellular DNA Traps Ramos-Martínez, Edgar Hernández-González, Leticia Ramos-Martínez, Iván Pérez-Campos Mayoral, Laura López-Cortés, Georgina I. Pérez-Campos, Eduardo Mayoral Andrade, Gabriel Hernández-Huerta, María Teresa José, Marco V. Front Immunol Immunology Extracellular DNA traps (ETs) are evolutionarily conserved antimicrobial mechanisms present in protozoa, plants, and animals. In this review, we compare their similarities in species of different taxa, and put forward the hypothesis that ETs have multiple origins. Our results are consistent with a process of evolutionary convergence in multicellular organisms through the application of a congruency test. Furthermore, we discuss why multicellularity is related to the presence of a mechanism initiating the formation of ETs. Frontiers Media S.A. 2021-02-24 /pmc/articles/PMC7943724/ /pubmed/33717121 http://dx.doi.org/10.3389/fimmu.2021.621311 Text en Copyright © 2021 Ramos-Martínez, Hernández-González, Ramos-Martínez, Pérez-Campos Mayoral, López-Cortés, Pérez-Campos, Mayoral Andrade, Hernández-Huerta and José http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Ramos-Martínez, Edgar
Hernández-González, Leticia
Ramos-Martínez, Iván
Pérez-Campos Mayoral, Laura
López-Cortés, Georgina I.
Pérez-Campos, Eduardo
Mayoral Andrade, Gabriel
Hernández-Huerta, María Teresa
José, Marco V.
Multiple Origins of Extracellular DNA Traps
title Multiple Origins of Extracellular DNA Traps
title_full Multiple Origins of Extracellular DNA Traps
title_fullStr Multiple Origins of Extracellular DNA Traps
title_full_unstemmed Multiple Origins of Extracellular DNA Traps
title_short Multiple Origins of Extracellular DNA Traps
title_sort multiple origins of extracellular dna traps
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943724/
https://www.ncbi.nlm.nih.gov/pubmed/33717121
http://dx.doi.org/10.3389/fimmu.2021.621311
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