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Proteasome-Generated cis-Spliced Peptides and Their Potential Role in CD8(+) T Cell Tolerance

The human immune system relies on the capability of CD8(+) T cells to patrol body cells, spot infected cells and eliminate them. This cytotoxic response is supposed to be limited to infected cells to avoid killing of healthy cells. To enable this, CD8(+) T cells have T Cell Receptors (TCRs) which sh...

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Detalles Bibliográficos
Autores principales: Mansurkhodzhaev, Artem, Barbosa, Camila R. R., Mishto, Michele, Liepe, Juliane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943738/
https://www.ncbi.nlm.nih.gov/pubmed/33717099
http://dx.doi.org/10.3389/fimmu.2021.614276