NOTCH and EZH2 collaborate to repress PTEN expression in breast cancer

Downregulation of the PTEN tumor suppressor transcript is frequent in breast cancer and associates with poor prognosis and triple-negative breast cancer (TNBC) when comparing breast cancers to one another. Here we show that in almost all cases, when comparing breast tumors to adjacent normal ducts,...

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Detalles Bibliográficos
Autores principales: Pappas, Kyrie, Martin, Tiphaine C., Wolfe, Andrew L., Nguyen, Christie B., Su, Tao, Jin, Jian, Hibshoosh, Hanina, Parsons, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943788/
https://www.ncbi.nlm.nih.gov/pubmed/33750924
http://dx.doi.org/10.1038/s42003-021-01825-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943788/
https://www.ncbi.nlm.nih.gov/pubmed/33750924
http://dx.doi.org/10.1038/s42003-021-01825-8

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