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The Deubiquitinating Enzyme UCHL1 Induces Resistance to Doxorubicin in HER2+ Breast Cancer by Promoting Free Fatty Acid Synthesis
Ubiquitin C-terminal hydrolase L1 (UCHL1), which is a deubiquitinating enzyme, is known to play a role in chemoresistance in cancers. However, its potential roles and mechanisms in the chemoresistance of breast cancer (BC) remain unclear. In this study, we examined its expression in patients with BC...
Autores principales: | Lu, Guangxian, Li, Jianhua, Ding, Leyun, Wang, Chenping, Tang, Lian, Liu, Xin, Xu, Jinhui, Zhou, Qin, Sun, Jiantong, Wang, Wenjuan, Ding, Xinyuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943833/ https://www.ncbi.nlm.nih.gov/pubmed/33718207 http://dx.doi.org/10.3389/fonc.2021.629640 |
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