Case Report: Detection of a Novel Germline PALB2 Deletion in a Young Woman With Hereditary Breast Cancer: When the Patient's Phenotype History Doesn't Lie

The partner and localizer of BRCA2 (PALB2) is a major BRCA2 binding partner that participates in homologous recombination repair in response to DNA double-strand breaks. Germline alterations of the PALB2 gene have recently been associated with a high risk of developing breast cancer. We investigated...

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Detalles Bibliográficos
Autores principales: De Angelis, Carmine, Nardelli, Carmela, Concolino, Paola, Pagliuca, Martina, Setaro, Mario, De Paolis, Elisa, De Placido, Pietro, Forestieri, Valeria, Scaglione, Giovanni Luca, Ranieri, Annalisa, Lombardo, Barbara, Pastore, Lucio, De Placido, Sabino, Capoluongo, Ettore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943848/
https://www.ncbi.nlm.nih.gov/pubmed/33718150
http://dx.doi.org/10.3389/fonc.2021.602523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943848/
https://www.ncbi.nlm.nih.gov/pubmed/33718150
http://dx.doi.org/10.3389/fonc.2021.602523

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