mtROS-mediated Akt/AMPK/mTOR pathway was involved in Copper-induced autophagy and it attenuates Copper-induced apoptosis in RAW264.7 mouse monocytes

Copper (Cu) is a trace element necessary in animals as well as human beings. However, excessive Cu is toxic to immunocytes, but the precise mechanism is largely unclear so far. This work was conducted aiming to examine the Cu-mediated autophagy mechanism together with its role in Cu toxicology in RA...

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Detalles Bibliográficos
Autores principales: Luo, Qin, Son, Yuzhen, Kang, Jingjing, Wu, Yuchen, Wu, Fengsun, Li, Yueqin, Dong, Qing, Wang, Jun, Song, Chao, Guo, Hongrui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944049/
https://www.ncbi.nlm.nih.gov/pubmed/33706171
http://dx.doi.org/10.1016/j.redox.2021.101912

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