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Role of Active Components of Medicinal Food in the Regulation of Angiogenesis

Angiogenesis refers to the formation of new blood vessels from the endothelial cells of existing arteries, veins, and capillaries. Angiogenesis is involved in a variety of physiological and pathological processes, such as the formation of malignant and development of atherosclerosis and other diseas...

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Autores principales: Pan, Dezhi, Gong, Xue, Wang, Xiaoqin, Li, Minhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944143/
https://www.ncbi.nlm.nih.gov/pubmed/33716724
http://dx.doi.org/10.3389/fphar.2020.594050
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author Pan, Dezhi
Gong, Xue
Wang, Xiaoqin
Li, Minhui
author_facet Pan, Dezhi
Gong, Xue
Wang, Xiaoqin
Li, Minhui
author_sort Pan, Dezhi
collection PubMed
description Angiogenesis refers to the formation of new blood vessels from the endothelial cells of existing arteries, veins, and capillaries. Angiogenesis is involved in a variety of physiological and pathological processes, such as the formation of malignant and development of atherosclerosis and other diseases. In recent years, many studies have shown that the active components of food have a certain regulatory effect on angiogenesis and negligible clinical limitations. With the increasing attention being paid to medicine and food homology, exploring the effect of active food components on angiogenesis is of great significance. In this review, we discuss the source, composition, pharmacological activity, and mechanism of action of certain active components of medicinal foods in detail. These could help prevent angiogenesis-related complications or provide a basis for healthier dietary habits. This review can provide a theoretical basis for the research and development of highly efficient anti-angiogenic drugs with low toxicity.
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spelling pubmed-79441432021-03-11 Role of Active Components of Medicinal Food in the Regulation of Angiogenesis Pan, Dezhi Gong, Xue Wang, Xiaoqin Li, Minhui Front Pharmacol Pharmacology Angiogenesis refers to the formation of new blood vessels from the endothelial cells of existing arteries, veins, and capillaries. Angiogenesis is involved in a variety of physiological and pathological processes, such as the formation of malignant and development of atherosclerosis and other diseases. In recent years, many studies have shown that the active components of food have a certain regulatory effect on angiogenesis and negligible clinical limitations. With the increasing attention being paid to medicine and food homology, exploring the effect of active food components on angiogenesis is of great significance. In this review, we discuss the source, composition, pharmacological activity, and mechanism of action of certain active components of medicinal foods in detail. These could help prevent angiogenesis-related complications or provide a basis for healthier dietary habits. This review can provide a theoretical basis for the research and development of highly efficient anti-angiogenic drugs with low toxicity. Frontiers Media S.A. 2021-01-22 /pmc/articles/PMC7944143/ /pubmed/33716724 http://dx.doi.org/10.3389/fphar.2020.594050 Text en Copyright © 2021 Pan, Gong, Wang and Li. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Pan, Dezhi
Gong, Xue
Wang, Xiaoqin
Li, Minhui
Role of Active Components of Medicinal Food in the Regulation of Angiogenesis
title Role of Active Components of Medicinal Food in the Regulation of Angiogenesis
title_full Role of Active Components of Medicinal Food in the Regulation of Angiogenesis
title_fullStr Role of Active Components of Medicinal Food in the Regulation of Angiogenesis
title_full_unstemmed Role of Active Components of Medicinal Food in the Regulation of Angiogenesis
title_short Role of Active Components of Medicinal Food in the Regulation of Angiogenesis
title_sort role of active components of medicinal food in the regulation of angiogenesis
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944143/
https://www.ncbi.nlm.nih.gov/pubmed/33716724
http://dx.doi.org/10.3389/fphar.2020.594050
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