Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl‐2/caspase‐3 pathway

Cachexia, characterized by loss of skeletal muscle mass and function, is estimated to inflict the majority of patients with oesophageal squamous cell carcinoma (ESCC) and associated with their poor prognosis. However, its underlying mechanisms remain elusive. Here, we developed an ESCC‐induced cache...

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Detalles Bibliográficos
Autores principales: Gao, Xiaohan, Wang, Yan, Lu, Fang, Chen, Xu, Yang, Di, Cao, Yiren, Zhang, Weimin, Chen, Jie, Zheng, Leilei, Wang, Guangchao, Fu, Ming, Ma, Liying, Song, Yongmei, Zhan, Qimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944388/
https://www.ncbi.nlm.nih.gov/pubmed/33732415
http://dx.doi.org/10.1002/jev2.12060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944388/
https://www.ncbi.nlm.nih.gov/pubmed/33732415
http://dx.doi.org/10.1002/jev2.12060

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