A promising new γ-secretase modulator for Alzheimer’s disease

Effective and safe treatments for Alzheimer’s disease (AD) have been an elusive target for scientists who have been working tirelessly to gain control over a disease that is affecting millions of people, with continually rising case numbers as the population ages. However, in this issue of JEM, Ryne...

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Detalles Bibliográficos
Autores principales: Dobrowolska Zakaria, Justyna A., Vassar, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Insights
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944409/
https://www.ncbi.nlm.nih.gov/pubmed/33683299
http://dx.doi.org/10.1084/jem.20210077
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author Dobrowolska Zakaria, Justyna A.
Vassar, Robert J.
author_facet Dobrowolska Zakaria, Justyna A.
Vassar, Robert J.
author_sort Dobrowolska Zakaria, Justyna A.
collection PubMed
description Effective and safe treatments for Alzheimer’s disease (AD) have been an elusive target for scientists who have been working tirelessly to gain control over a disease that is affecting millions of people, with continually rising case numbers as the population ages. However, in this issue of JEM, Rynearson et al. (2021. J. Exp. Med. https://doi.org/10.1084/jem.20202560) present a beacon of hope for this field with a preclinical evaluation of a potent and robust γ-secretase modulator (GSM).
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spelling pubmed-79444092021-10-05 A promising new γ-secretase modulator for Alzheimer’s disease Dobrowolska Zakaria, Justyna A. Vassar, Robert J. J Exp Med Insights Effective and safe treatments for Alzheimer’s disease (AD) have been an elusive target for scientists who have been working tirelessly to gain control over a disease that is affecting millions of people, with continually rising case numbers as the population ages. However, in this issue of JEM, Rynearson et al. (2021. J. Exp. Med. https://doi.org/10.1084/jem.20202560) present a beacon of hope for this field with a preclinical evaluation of a potent and robust γ-secretase modulator (GSM). Rockefeller University Press 2021-03-08 /pmc/articles/PMC7944409/ /pubmed/33683299 http://dx.doi.org/10.1084/jem.20210077 Text en © 2021 Dobrowolska Zakaria and Vassar http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Insights
Dobrowolska Zakaria, Justyna A.
Vassar, Robert J.
A promising new γ-secretase modulator for Alzheimer’s disease
title A promising new γ-secretase modulator for Alzheimer’s disease
title_full A promising new γ-secretase modulator for Alzheimer’s disease
title_fullStr A promising new γ-secretase modulator for Alzheimer’s disease
title_full_unstemmed A promising new γ-secretase modulator for Alzheimer’s disease
title_short A promising new γ-secretase modulator for Alzheimer’s disease
title_sort promising new γ-secretase modulator for alzheimer’s disease
topic Insights
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944409/
https://www.ncbi.nlm.nih.gov/pubmed/33683299
http://dx.doi.org/10.1084/jem.20210077
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