Simian-Human Immunodeficiency Virus SHIV.C.CH505 Persistence in ART-Suppressed Infant Macaques Is Characterized by Elevated SHIV RNA in the Gut and a High Abundance of Intact SHIV DNA in Naive CD4(+) T Cells

Mother-to-child transmission of human immunodeficiency virus type 1 (HIV-1) continues to cause new pediatric cases of infection through breastfeeding, a setting where it is not always possible to initiate early antiretroviral therapy (ART). Without novel interventions that do not rely on daily ART,...

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Detalles Bibliográficos
Autores principales: Obregon-Perko, Veronica, Bricker, Katherine M., Mensah, Gloria, Uddin, Ferzan, Kumar, Mithra R., Fray, Emily J., Siliciano, Robert F., Schoof, Nils, Horner, Anna, Mavigner, Maud, Liang, Shan, Vanderford, Thomas, Sass, Julian, Chan, Cliburn, Berendam, Stella J., Bar, Katharine J., Shaw, George M., Silvestri, Guido, Fouda, Genevieve G., Permar, Sallie R., Chahroudi, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Pathogenesis and Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944446/
https://www.ncbi.nlm.nih.gov/pubmed/33087463
http://dx.doi.org/10.1128/JVI.01669-20

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