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Thermovaccination: Thermoheliox as an Immune Response Stimulant. Kinetics of Antibodies and C-Reactive Protein Synthesis in Coronaviral Infection

The high efficiency of using thermoheliox (inhalation with a high-temperature mixture of helium and oxygen) in the treatment of patients affected by COVID-19 was shown. The dynamics of accumulation of IgG, IgM, and C-reactive protein (CRP) in patients with coronavirus infection in the “working” and...

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Autores principales: Varfolomeev, S. D., Zhuravel, S. V., Panin, A. A., Shogenova, L. V., Bykov, V. I., Tsybenova, S. B., Ryabokon, A. M., Utkina, I. I., Gavrilov, P. V., Chuchalin, A. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pleiades Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944475/
https://www.ncbi.nlm.nih.gov/pubmed/33689074
http://dx.doi.org/10.1134/S1607672921010129
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author Varfolomeev, S. D.
Zhuravel, S. V.
Panin, A. A.
Shogenova, L. V.
Bykov, V. I.
Tsybenova, S. B.
Ryabokon, A. M.
Utkina, I. I.
Gavrilov, P. V.
Chuchalin, A. G.
author_facet Varfolomeev, S. D.
Zhuravel, S. V.
Panin, A. A.
Shogenova, L. V.
Bykov, V. I.
Tsybenova, S. B.
Ryabokon, A. M.
Utkina, I. I.
Gavrilov, P. V.
Chuchalin, A. G.
author_sort Varfolomeev, S. D.
collection PubMed
description The high efficiency of using thermoheliox (inhalation with a high-temperature mixture of helium and oxygen) in the treatment of patients affected by COVID-19 was shown. The dynamics of accumulation of IgG, IgM, and C-reactive protein (CRP) in patients with coronavirus infection in the “working” and control groups was studied experimentally. It was shown that thermoheliox intensifies the synthesis of IgG, IgM, and CRP antibodies, while eliminating the induction period on the kinetic curves of the synthesis of specific antibodies in the IgG form and transfers the synthesis of CRP to a fast phase. The results of experiments confirm the previously obtained data based on the analysis of the kinetic model of the development of coronaviral infection in the human body.
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spelling pubmed-79444752021-03-10 Thermovaccination: Thermoheliox as an Immune Response Stimulant. Kinetics of Antibodies and C-Reactive Protein Synthesis in Coronaviral Infection Varfolomeev, S. D. Zhuravel, S. V. Panin, A. A. Shogenova, L. V. Bykov, V. I. Tsybenova, S. B. Ryabokon, A. M. Utkina, I. I. Gavrilov, P. V. Chuchalin, A. G. Dokl Biochem Biophys Biochemistry, Biophysics, and Molecular Biology The high efficiency of using thermoheliox (inhalation with a high-temperature mixture of helium and oxygen) in the treatment of patients affected by COVID-19 was shown. The dynamics of accumulation of IgG, IgM, and C-reactive protein (CRP) in patients with coronavirus infection in the “working” and control groups was studied experimentally. It was shown that thermoheliox intensifies the synthesis of IgG, IgM, and CRP antibodies, while eliminating the induction period on the kinetic curves of the synthesis of specific antibodies in the IgG form and transfers the synthesis of CRP to a fast phase. The results of experiments confirm the previously obtained data based on the analysis of the kinetic model of the development of coronaviral infection in the human body. Pleiades Publishing 2021-03-10 2021 /pmc/articles/PMC7944475/ /pubmed/33689074 http://dx.doi.org/10.1134/S1607672921010129 Text en © Pleiades Publishing, Ltd. 2021, ISSN 1607-6729, Doklady Biochemistry and Biophysics, 2021, Vol. 496, pp. 44–47. © Pleiades Publishing, Ltd., 2021.Russian Text © The Author(s), 2021, published in Doklady Rossiiskoi Akademii Nauk. Nauki o Zhizni, 2021, Vol. 496, pp. 94–98. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Biochemistry, Biophysics, and Molecular Biology
Varfolomeev, S. D.
Zhuravel, S. V.
Panin, A. A.
Shogenova, L. V.
Bykov, V. I.
Tsybenova, S. B.
Ryabokon, A. M.
Utkina, I. I.
Gavrilov, P. V.
Chuchalin, A. G.
Thermovaccination: Thermoheliox as an Immune Response Stimulant. Kinetics of Antibodies and C-Reactive Protein Synthesis in Coronaviral Infection
title Thermovaccination: Thermoheliox as an Immune Response Stimulant. Kinetics of Antibodies and C-Reactive Protein Synthesis in Coronaviral Infection
title_full Thermovaccination: Thermoheliox as an Immune Response Stimulant. Kinetics of Antibodies and C-Reactive Protein Synthesis in Coronaviral Infection
title_fullStr Thermovaccination: Thermoheliox as an Immune Response Stimulant. Kinetics of Antibodies and C-Reactive Protein Synthesis in Coronaviral Infection
title_full_unstemmed Thermovaccination: Thermoheliox as an Immune Response Stimulant. Kinetics of Antibodies and C-Reactive Protein Synthesis in Coronaviral Infection
title_short Thermovaccination: Thermoheliox as an Immune Response Stimulant. Kinetics of Antibodies and C-Reactive Protein Synthesis in Coronaviral Infection
title_sort thermovaccination: thermoheliox as an immune response stimulant. kinetics of antibodies and c-reactive protein synthesis in coronaviral infection
topic Biochemistry, Biophysics, and Molecular Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944475/
https://www.ncbi.nlm.nih.gov/pubmed/33689074
http://dx.doi.org/10.1134/S1607672921010129
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