The long noncoding RNA MALAT1 modulates adipose loss in cancer-associated cachexia by suppressing adipogenesis through PPAR-γ

BACKGROUND: Cancer-associated cachexia is a multifactorial syndrome defined by progressive weight loss with ongoing loss of adipose tissue and skeletal muscle. Adipose loss occurs in the early stage of cachexia and is associated with reduced quality of life and survival time. Although numerous lncRN...

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Detalles Bibliográficos
Autores principales: Han, Jun, Shen, Lei, Zhan, Zheng, Liu, Yuguo, Zhang, Chang, Guo, Ruochen, Luo, Yangjun, Xie, Zhiqin, Feng, Ying, Wu, Guohao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944636/
https://www.ncbi.nlm.nih.gov/pubmed/33691715
http://dx.doi.org/10.1186/s12986-021-00557-0

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