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Is there a relation between clinical scores and serum ion levels after MoM-THA? One year results in 383 implants

BACKGROUND AND AIM OF THE WORK: Adverse reaction to metal debris is the major cause of the high revision rates of metal on metal hip implants with femoral head size ≥ 36mm. Health authorities recommend regular surveillance even for asymptomatic individuals. The main investigations used are Co+ and C...

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Autores principales: Pogliacomi, Francesco, Schiavi, Paolo, Calderazzi, Filippo, Leigheb, Massimiliano, Domenichini, Marco, Pedrazzini, Alessio, Ceccarelli, Francesco, Vaienti, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mattioli 1885 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944688/
https://www.ncbi.nlm.nih.gov/pubmed/33559629
http://dx.doi.org/10.23750/abm.v91i14-S.10955
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author Pogliacomi, Francesco
Schiavi, Paolo
Calderazzi, Filippo
Leigheb, Massimiliano
Domenichini, Marco
Pedrazzini, Alessio
Ceccarelli, Francesco
Vaienti, Enrico
author_facet Pogliacomi, Francesco
Schiavi, Paolo
Calderazzi, Filippo
Leigheb, Massimiliano
Domenichini, Marco
Pedrazzini, Alessio
Ceccarelli, Francesco
Vaienti, Enrico
author_sort Pogliacomi, Francesco
collection PubMed
description BACKGROUND AND AIM OF THE WORK: Adverse reaction to metal debris is the major cause of the high revision rates of metal on metal hip implants with femoral head size ≥ 36mm. Health authorities recommend regular surveillance even for asymptomatic individuals. The main investigations used are Co+ and Cr+ serum levels, x-rays and, eventually, ultrasound and MARS-MRI. Clinic is also assessed. The aim of this study is to identify if there is a relation between ion levels and the clinical scores in order to evaluate the outcome and plan the correct management after this type of implant. METHODS: 383 subjects were included and divided in 3 groups (serum ion levels >, < and >60 µg/L). Co+, Cr+, HHS and OHS results of 1 year (2017) were analysed in order to show a correlation between ion levels and clinical scores. RESULTS: Clinical scores were similar in group 1 and 2. Differences were observed comparing the group 1 and 2 with group 3 for both variables. DISCUSSION AND CONCLUSIONS: Surveillance algorithms have been introduced by health authorities. Nevertheless, the indication to revision surgery is not simple especially in those cases in which a discrepancy between clinic and investigations is present. In this study clinical scores seem to be less important than ion levels in the evaluation of outcomes and in order to plan the correct management in the majority of cases. Larger studies are needed to highlight the real importance of clinical scores in the decision making after these type of implants.
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spelling pubmed-79446882021-03-10 Is there a relation between clinical scores and serum ion levels after MoM-THA? One year results in 383 implants Pogliacomi, Francesco Schiavi, Paolo Calderazzi, Filippo Leigheb, Massimiliano Domenichini, Marco Pedrazzini, Alessio Ceccarelli, Francesco Vaienti, Enrico Acta Biomed Original Article BACKGROUND AND AIM OF THE WORK: Adverse reaction to metal debris is the major cause of the high revision rates of metal on metal hip implants with femoral head size ≥ 36mm. Health authorities recommend regular surveillance even for asymptomatic individuals. The main investigations used are Co+ and Cr+ serum levels, x-rays and, eventually, ultrasound and MARS-MRI. Clinic is also assessed. The aim of this study is to identify if there is a relation between ion levels and the clinical scores in order to evaluate the outcome and plan the correct management after this type of implant. METHODS: 383 subjects were included and divided in 3 groups (serum ion levels >, < and >60 µg/L). Co+, Cr+, HHS and OHS results of 1 year (2017) were analysed in order to show a correlation between ion levels and clinical scores. RESULTS: Clinical scores were similar in group 1 and 2. Differences were observed comparing the group 1 and 2 with group 3 for both variables. DISCUSSION AND CONCLUSIONS: Surveillance algorithms have been introduced by health authorities. Nevertheless, the indication to revision surgery is not simple especially in those cases in which a discrepancy between clinic and investigations is present. In this study clinical scores seem to be less important than ion levels in the evaluation of outcomes and in order to plan the correct management in the majority of cases. Larger studies are needed to highlight the real importance of clinical scores in the decision making after these type of implants. Mattioli 1885 2020 2020-12-30 /pmc/articles/PMC7944688/ /pubmed/33559629 http://dx.doi.org/10.23750/abm.v91i14-S.10955 Text en Copyright: © 2020 ACTA BIO MEDICA SOCIETY OF MEDICINE AND NATURAL SCIENCES OF PARMA http://creativecommons.org/licenses/by-nc-sa/4.0 This work is licensed under a Creative Commons Attribution 4.0 International License
spellingShingle Original Article
Pogliacomi, Francesco
Schiavi, Paolo
Calderazzi, Filippo
Leigheb, Massimiliano
Domenichini, Marco
Pedrazzini, Alessio
Ceccarelli, Francesco
Vaienti, Enrico
Is there a relation between clinical scores and serum ion levels after MoM-THA? One year results in 383 implants
title Is there a relation between clinical scores and serum ion levels after MoM-THA? One year results in 383 implants
title_full Is there a relation between clinical scores and serum ion levels after MoM-THA? One year results in 383 implants
title_fullStr Is there a relation between clinical scores and serum ion levels after MoM-THA? One year results in 383 implants
title_full_unstemmed Is there a relation between clinical scores and serum ion levels after MoM-THA? One year results in 383 implants
title_short Is there a relation between clinical scores and serum ion levels after MoM-THA? One year results in 383 implants
title_sort is there a relation between clinical scores and serum ion levels after mom-tha? one year results in 383 implants
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944688/
https://www.ncbi.nlm.nih.gov/pubmed/33559629
http://dx.doi.org/10.23750/abm.v91i14-S.10955
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