Combined in silico and in vitro approaches identified the antipsychotic drug lurasidone and the antiviral drug elbasvir as SARS-CoV2 and HCoV-OC43 inhibitors

The current emergency of the novel coronavirus SARS-CoV2 urged the need for broad-spectrum antiviral drugs as the first line of treatment. Coronaviruses are a large family of viruses that already challenged humanity in at least two other previous outbreaks and are likely to be a constant threat for...

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Detalles Bibliográficos
Autores principales: Milani, Mario, Donalisio, Manuela, Bonotto, Rafaela Milan, Schneider, Edoardo, Arduino, Irene, Boni, Francesco, Lembo, David, Marcello, Alessandro, Mastrangelo, Eloise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier B.V. 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944860/
https://www.ncbi.nlm.nih.gov/pubmed/33713730
http://dx.doi.org/10.1016/j.antiviral.2021.105055

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