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Effects of N-Linked Glycan on Lassa Virus Envelope Glycoprotein Cleavage, Infectivity, and Immune Response

Lassa virus (LASV) belongs to the Mammarenavirus genus (family Arenaviridae) and causes severe hemorrhagic fever in humans. The glycoprotein complex (GPC) contains eleven N-linked glycans that play essential roles in GPC functionalities such as cleavage, transport, receptor recognition, epitope shie...

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Detalles Bibliográficos
Autores principales: Zhu, Xueqin, Liu, Yang, Guo, Jiao, Cao, Junyuan, Wang, Zonglin, Xiao, Gengfu, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7945000/
https://www.ncbi.nlm.nih.gov/pubmed/33689141
http://dx.doi.org/10.1007/s12250-021-00358-y

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