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Effects of N-Linked Glycan on Lassa Virus Envelope Glycoprotein Cleavage, Infectivity, and Immune Response
Lassa virus (LASV) belongs to the Mammarenavirus genus (family Arenaviridae) and causes severe hemorrhagic fever in humans. The glycoprotein complex (GPC) contains eleven N-linked glycans that play essential roles in GPC functionalities such as cleavage, transport, receptor recognition, epitope shie...
Autores principales: | Zhu, Xueqin, Liu, Yang, Guo, Jiao, Cao, Junyuan, Wang, Zonglin, Xiao, Gengfu, Wang, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7945000/ https://www.ncbi.nlm.nih.gov/pubmed/33689141 http://dx.doi.org/10.1007/s12250-021-00358-y |
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