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Exosomes for mRNA delivery: a novel biotherapeutic strategy with hurdles and hope

Over the past decade, therapeutic messenger RNAs (mRNAs) have emerged as a highly promising new class of drugs for protein replacement therapies. Due to the recent developments, the incorporation of modified nucleotides in synthetic mRNAs can lead to maximizing protein expression and reducing advers...

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Detalles Bibliográficos
Autores principales: Aslan, Cynthia, Kiaie, Seyed Hossein, Zolbanin, Naime Majidi, Lotfinejad, Parisa, Ramezani, Reihaneh, Kashanchi, Fatah, Jafari, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7945253/
https://www.ncbi.nlm.nih.gov/pubmed/33691652
http://dx.doi.org/10.1186/s12896-021-00683-w