Cargando…

MiRNA-132 regulates the development of osteoarthritis in correlation with the modulation of PTEN/PI3K/AKT signaling

BACKGROUND: Osteoarthritis (OA) is a commonly known prevalent joint disease, with limited therapeutic methods. This study aimed to investigate the functions of miRNA-132 (miR-132) in the modulation of PTEN/PI3K/AKT signaling pathway in the development and progression of osteoarthritis. METHODS: Eigh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Wei, Hu, Chengfang, Zhang, Chi, Luo, Congfeng, Zhong, Biao, Yu, Xiaowei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7945330/ https://www.ncbi.nlm.nih.gov/pubmed/33691628 http://dx.doi.org/10.1186/s12877-021-02046-8

Ejemplares similares

Circular RNA-CDR1as acts as the sponge of microRNA-641 to promote osteoarthritis progression
por: Zhang, Wei, et al.
Publicado: (2020)

miRNA-186 Improves Sepsis Induced Renal Injury Via PTEN/PI3K/AKT/P53 Pathway
por: Li, Min, et al.
Publicado: (2020)

miRNA-425-5p enhances lung cancer growth via the PTEN/PI3K/AKT signaling axis
por: Zhou, Jin-shan, et al.
Publicado: (2020)

miRNA-21 promotes osteogenesis via the PTEN/PI3K/Akt/HIF-1α pathway and enhances bone regeneration in critical size defects
por: Yang, Chi, et al.
Publicado: (2019)

miR‐373 regulates inflammatory cytokine‐mediated chondrocyte proliferation in osteoarthritis by targeting the P2X7 receptor
por: Zhang, Wei, et al.
Publicado: (2018)

靶向抑制miRNA-21对K562细胞增殖及PTEN-PI3K/AKT通路的影响
Publicado: (2016)

MiRNA-21 mediates the antiangiogenic activity of metformin through targeting PTEN and SMAD7 expression and PI3K/AKT pathway
por: Luo, Mao, et al.
Publicado: (2017)

Effect of miR-106b on Invasiveness of Pituitary Adenoma via PTEN-PI3K/AKT
por: Zheng, Zhiming, et al.
Publicado: (2017)

Correlation analysis of differentially expressed long non-coding RNA HOTAIR with PTEN/PI3K/AKT pathway and inflammation in patients with osteoarthritis and the effect of baicalin intervention
por: Chen, Xiaolu, et al.
Publicado: (2023)

PTENP1/miR-20a/PTEN axis contributes to breast cancer progression by regulating PTEN via PI3K/AKT pathway
por: Gao, Xue, et al.
Publicado: (2019)

MiR-132 controls pancreatic beta cell proliferation and survival through Pten/Akt/Foxo3 signaling
por: Mziaut, Hassan, et al.
Publicado: (2019)

Long Non-Coding RNA 691 Regulated PTEN/PI3K/AKT Signaling Pathway in Osteosarcoma Through miRNA-9-5p
por: Yao, Pengju, et al.
Publicado: (2020)

miR-26a-5p protects against myocardial ischemia/reperfusion injury by regulating the PTEN/PI3K/AKT signaling pathway
por: Xing, Xiaowei, et al.
Publicado: (2020)

miR-144-3p Contributes to the Development of Thyroid Tumors Through the PTEN/PI3K/AKT Pathway
por: Cao, Hui-Ling, et al.
Publicado: (2020)

Inhibition of the AKT/mTOR pathway negatively regulates PTEN expression via miRNAs: Effect of Akt/mTOR inhibition on PTEN expression
por: Wan, Linyan, et al.
Publicado: (2022)

Correction: PTENP1/miR-20a/PTEN axis contributes to breast cancer progression by regulating PTEN via PI3K/AKT pathway
por: Gao, Xue, et al.
Publicado: (2023)

The PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models
por: Carnero, Amancio, et al.
Publicado: (2014)

Dysregulation of PI3K/Akt/PTEN Pathway in Canine Mammary Tumor
por: Kim, Soo-Hyeon, et al.
Publicado: (2021)

miRNA-103 promotes chondrocyte apoptosis by down-regulation of Sphingosine kinase-1 and ameliorates PI3K/AKT pathway in osteoarthritis
por: Li, Fang, et al.
Publicado: (2019)

Circulating exosomal miR-21 mediates HUVEC proliferation and migration through PTEN/PI3K/AKT in Crohn’s disease
por: Xie, Xiaoran, et al.
Publicado: (2022)

Dysregulated plasma levels of miRNA-132 and miRNA-134 in patients with obsessive-compulsive disorder
por: Yue, Jihui, et al.
Publicado: (2020)

miR-494 promotes progression of retinoblastoma via PTEN through PI3K/AKT signaling pathway
por: Xu, Fen, et al.
Publicado: (2020)

PTEN regulation of the proliferation and differentiation of auditory progenitors through the PTEN/PI3K/Akt-signaling pathway in mice
por: Sun, Chen, et al.
Publicado: (2014)

PI3K/AKT/PTEN Signaling as a Molecular Target in Leukemia Angiogenesis
por: Okumura, Naoko, et al.
Publicado: (2012)

Roles of PI3K/AKT/PTEN Pathway as a Target for Pharmaceutical Therapy
por: Matsuda, Satoru, et al.
Publicado: (2013)

PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis
por: Lee, Min-Sik, et al.
Publicado: (2015)

Inhibition of miR-19a partially reversed the resistance of colorectal cancer to oxaliplatin via PTEN/PI3K/AKT pathway
por: Zhang, Ye, et al.
Publicado: (2020)

MiR-106b induces cell radioresistance via the PTEN/PI3K/AKT pathways and p21 in colorectal cancer
por: Zheng, Lin, et al.
Publicado: (2015)

miR-214 targets the PTEN-mediated PI3K/Akt signaling pathway and regulates cell proliferation and apoptosis in ovarian cancer
por: Liu, Jing, et al.
Publicado: (2017)

PTEN modulates neurites outgrowth and neuron apoptosis involving the PI3K/Akt/mTOR signaling pathway
por: Liu, Shen, et al.
Publicado: (2019)

Overexpression of GATA4 enhances the antiapoptotic effect of exosomes secreted from cardiac colony-forming unit fibroblasts via miRNA221-mediated targeting of the PTEN/PI3K/AKT signaling pathway
por: Hao, Chunshu, et al.
Publicado: (2020)

Notoginsenoside R7 suppresses cervical cancer via PI3K/PTEN/Akt/mTOR signaling
por: Li, Li, et al.
Publicado: (2017)

PTEN lipid phosphatase inactivation links the hippo and PI3K/Akt pathways to induce gastric tumorigenesis
por: Xu, Wenting, et al.
Publicado: (2018)

Critical implication of the PTEN/PI3K/AKT pathway during BMP2-induced heterotopic ossification
por: Dong, Jun, et al.
Publicado: (2021)

Knockdown of miR-214 Alleviates Renal Interstitial Fibrosis by Targeting the Regulation of the PTEN/PI3K/AKT Signalling Pathway
por: Hou, DongHua, et al.
Publicado: (2022)

miR-23b-3p regulates differentiation of osteoclasts by targeting PTEN via the PI3k/AKT pathway
por: Chai, Jiwei, et al.
Publicado: (2019)

The PI3K/AKT signaling pathway: Associations of miRNAs with dysregulated gene expression in colorectal cancer
por: Slattery, Martha L., et al.
Publicado: (2017)

[Retracted] SIRT1 promotes tumorigenesis of hepatocellular carcinoma through PI3K/PTEN/AKT signaling
por: Wang, Hanning, et al.
Publicado: (2023)

Regulation of the PTEN/PI3K/AKT pathway in RCC using the active compounds of natural products in vitro
por: Wang, Xue, et al.
Publicado: (2021)

miRNA-125a modulates autophagy of thyroiditis through PI3K/Akt/mTOR signaling pathway
por: Chen, Danyan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ilbmcpokt2upgbijnbaftts0dl