Normal levels of KIF5 but reduced KLC1 levels in both Alzheimer disease and Alzheimer disease in Down syndrome: evidence suggesting defects in anterograde transport

BACKGROUND: Impaired axonal transport may contribute to the pathogenesis of neurodegenerative diseases, including Alzheimer’s disease (AD) and Down syndrome (DS). Axonal transport is a complex process in which specific motor proteins move cargoes to and from neuronal cell bodies and their processes....

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Detalles Bibliográficos
Autores principales: Chen, Xu-Qiao, Das, Utpal, Park, Gooho, Mobley, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7945332/
https://www.ncbi.nlm.nih.gov/pubmed/33691783
http://dx.doi.org/10.1186/s13195-021-00796-6

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