Loss of 5-Hydroxymethylcytosine as an Epigenetic Signature That Correlates With Poor Outcomes in Patients With Medulloblastoma

Medulloblastoma, as the most common malignant brain tumor in children, exhibits highly dysregulated DNA methylation. The novel epigenetic marker—5-hydroxymethylcytosine (5hmC) plays essential role in gene regulation during brain development and in brain tumors. However, the biological and clinical i...

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Detalles Bibliográficos
Autores principales: Zhao, Fu, Zhang, Zhi-Wei, Zhang, Jing, Zhang, Shun, Zhang, Heng, Zhao, Chi, Chen, Yang, Luo, Lin, Tong, Wei-Min, Li, Chunde, Niu, Yamei, Liu, Pinan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7945595/
https://www.ncbi.nlm.nih.gov/pubmed/33718152
http://dx.doi.org/10.3389/fonc.2021.603686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7945595/
https://www.ncbi.nlm.nih.gov/pubmed/33718152
http://dx.doi.org/10.3389/fonc.2021.603686

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